Suppr超能文献

老年人外出时间与认知、身体和情绪健康:纵向混合效应模型

Time Out-of-Home and Cognitive, Physical, and Emotional Wellbeing of Older Adults: A Longitudinal Mixed Effects Model.

作者信息

Petersen Johanna, Austin Daniel, Mattek Nora, Kaye Jeffrey

机构信息

Department of Biomedical Engineering, Oregon Health & Science University, Portland, OR, United States of America.

Department of Neurology, Oregon Health & Science University, Portland, OR, United States of America.

出版信息

PLoS One. 2015 Oct 5;10(10):e0139643. doi: 10.1371/journal.pone.0139643. eCollection 2015.

Abstract

BACKGROUND

Time out-of-home has been linked with numerous health outcomes, including cognitive decline, poor physical ability and low emotional state. Comprehensive characterization of this important health metric would potentially enable objective monitoring of key health outcomes. The objective of this study is to determine the relationship between time out-of-home and cognitive status, physical ability and emotional state.

METHODS AND FINDINGS

Participants included 85 independent older adults, age 65-96 years (M = 86.36; SD = 6.79) who lived alone, from the Intelligent Systems for Assessing Aging Changes (ISAAC) and the ORCATECH Life Laboratory cohorts. Factors hypothesized to affect time out-of-home were assessed on three different temporal levels: yearly (cognitive status, loneliness, clinical walking speed), weekly (pain and mood) or daily (time out-of-home, in-home walking speed, weather, and season). Subject characteristics including age, race, and gender were assessed at baseline. Total daily time out-of-home in hours was assessed objectively and unobtrusively for up to one year using an in-home activity sensor platform. A longitudinal tobit mixed effects regression model was used to relate daily time out-of-home to cognitive status, physical ability and emotional state. More hours spend outside the home was associated with better cognitive function as assessed using the Clinical Dementia Rating (CDR) Scale, where higher scores indicate lower cognitive function (βCDR = -1.69, p<0.001). More hours outside the home was also associated with superior physical ability (βPain = -0.123, p<0.001) and improved emotional state (βLonely = -0.046, p<0.001; βLow mood = -0.520, p<0.001). Weather, season, and weekday also affected the daily time out-of-home.

CONCLUSIONS

These results suggest that objective longitudinal monitoring of time out-of-home may enable unobtrusive assessment of cognitive, physical and emotional state. In addition, these results indicate that the factors affecting out-of-home behavior are complex, with factors such as living environment, weather and season significantly affecting time out-of-home. Studies investigating the relationship between time out-of-home and health outcomes may be optimized by taking into account the environment and life factors presented here.

摘要

背景

外出时间与众多健康结果相关,包括认知能力下降、身体能力差和情绪低落。对这一重要健康指标进行全面描述可能有助于对关键健康结果进行客观监测。本研究的目的是确定外出时间与认知状态、身体能力和情绪状态之间的关系。

方法与结果

参与者包括85名年龄在65 - 96岁(M = 86.36;SD = 6.79)的独立老年人,他们来自评估衰老变化的智能系统(ISAAC)和ORCATECH生活实验室队列,且均独自生活。假设会影响外出时间的因素在三个不同的时间层面进行评估:每年(认知状态、孤独感、临床步行速度)、每周(疼痛和情绪)或每天(外出时间、室内步行速度、天气和季节)。在基线时评估包括年龄、种族和性别的受试者特征。使用家庭活动传感器平台客观且不引人注意地评估长达一年的每日外出总时长(以小时为单位)。采用纵向受限混合效应回归模型将每日外出时间与认知状态、身体能力和情绪状态相关联。使用临床痴呆评定量表(CDR)评估发现,外出时间越长与更好的认知功能相关,其中得分越高表明认知功能越低(βCDR = -1.69,p<0.001)。外出时间越长还与更好的身体能力(β疼痛 = -0.123,p<0.001)和改善的情绪状态相关(β孤独 = -0.046,p<0.001;β情绪低落 = -0.520,p<0.001)。天气、季节和工作日也会影响每日外出时间。

结论

这些结果表明,对外出时间进行客观纵向监测可能有助于对认知、身体和情绪状态进行不引人注意的评估。此外,这些结果表明影响外出行为的因素很复杂,生活环境、天气和季节等因素会显著影响外出时间。考虑到此处呈现的环境和生活因素,研究外出时间与健康结果之间关系的研究可能会得到优化。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/242b/4593630/99370b6e9a01/pone.0139643.g001.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验