Molecular Imaging Center, National Taiwan University , Taipei , Taiwan.
Institute of Population Health Sciences, National Health Research Institutes , Miaoli , Taiwan.
Am J Hypertens. 2016 Nov 1;29(11):1283-1291. doi: 10.1093/ajh/hpv164.
Noninvasive brachial systolic blood pressure (nSBP-B) usually approaches invasive central systolic blood pressure (iSBP-C) with a high correlation. Whether nSBP-B is an accurate estimate of iSBP-C remained to be investigated. Thus, this study aimed to compare the errors of nSBP-B and noninvasive central systolic blood pressure (nSBP-C) with different techniques in estimating iSBP-C.
Simultaneous invasive high-fidelity central aortic pressure waveforms and the noninvasive left brachial pulse volume recording (PVR) waveform were recorded in a Generation group ( N = 40) and a Validation group ( N = 100). The accuracy of the noninvasive estimates of iSBP-C obtained from analysis of the calibrated PVR waveform using the generalized transfer function (GTF), pulse waveform analysis (PWA), and N-point moving average (NPMA) methods was examined in the Validation group by calculating the mean absolute error (MAE).
In Generation group, the MAE was 4.6±4.1mm Hg between nSBP-B and invasive brachial SBP, and 6.8±5.5mm Hg between nSBP-B and iSBP-C. In comparison, the MAE of between iSBP-C and nSBP-C with PWA, NPMA, and GTF were 5.5±4.5, 5.8±4.9, and 5.9±5.0mm Hg, respectively. In Validation group, the MAE of nSBP-B (6.9±4.6mm Hg) for estimating iSBP-C was significantly greater than that of PWA (5.0±3.4mm Hg) and NPMA (6.1±4.4mm Hg), and GTF (6.1±4.9mm Hg). The percentage of absolute band error ≤5mm Hg was 62% for nSBP-B, 69% for GTF, 83% for PWA, and 69% for NPMA.
The accuracy of nSBP-B was inferior to the n SBP-C measures in estimating iSBP-C.
无创肱动脉收缩压（nSBP-B）通常与有创中心收缩压（iSBP-C）高度相关。nSBP-B 是否能准确估计 iSBP-C 仍有待研究。因此，本研究旨在比较不同技术的 nSBP-B 和无创中心收缩压（nSBP-C）在估计 iSBP-C 时的误差。
在一代（N=40）和验证组（N=100）中同时记录有创高保真中心主动脉压力波形和无创左侧肱动脉脉搏容积记录（PVR）波形。使用广义传递函数（GTF）、脉搏波形分析（PWA）和 N 点移动平均（NPMA）方法分析校准后的 PVR 波形，得到 iSBP-C 的无创估计值，在验证组中通过计算平均绝对误差（MAE）来检验其准确性。
在一代中，nSBP-B 与有创肱动脉 SBP 之间的 MAE 为 4.6±4.1mmHg，nSBP-B 与 iSBP-C 之间的 MAE 为 6.8±5.5mmHg。相比之下，PWA、NPMA 和 GTF 法测量的 iSBP-C 与 nSBP-C 之间的 MAE 分别为 5.5±4.5mmHg、5.8±4.9mmHg 和 5.9±5.0mmHg。在验证组中，nSBP-B（6.9±4.6mmHg）估计 iSBP-C 的 MAE 明显大于 PWA（5.0±3.4mmHg）和 NPMA（6.1±4.4mmHg）和 GTF（6.1±4.9mmHg）。nSBP-B 的绝对带误差百分比≤5mmHg 的为 62%，GTF 为 69%，PWA 为 83%，NPMA 为 69%。
nSBP-B 估计 iSBP-C 的准确性不如 nSBP-C 测量。
