• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

基于问卷调查的随机病例对照研究：评估印度口服非那雄胺治疗雄激素性脱发患者的性功能

Randomized Questionnaire Based Case-Control Research Study on Evaluation of Sexual Function in Indian Patients Taking Oral Finasteride for Androgenetic Alopecia.

作者信息

Narasimhalu C R V

机构信息

Department of Skin and STD, Saveetha Medical College, Saveetha University, Saveetha Nagar, Thandalam, Kancheepuram, Tamil Nadu, 602105, India.

出版信息

Dermatol Ther (Heidelb). 2015 Dec;5(4):231-234. doi: 10.1007/s13555-015-0084-3. Epub 2015 Oct 5.

DOI:10.1007/s13555-015-0084-3
PMID:26438381
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4674453/
Abstract

INTRODUCTION

Finasteride is one of the most common drugs used in androgenetic alopecia. The literature discusses the sexual side effects of the drug; however, in practice there is little evidence to support this. The aim of the present study was to investigate the sexual dysfunction in patients taking finasteride 1 mg for androgenetic alopecia.

METHODS

A questionnaire, based on the International Index of Erectile Function, was given to approximately 586 patients with androgenetic alopecia who were being treated with finasteride 1 mg for an average of 16 weeks. These patients were compared to an age-related control group who were attending the Dermatology Out Patients Department for various other skin ailments not related to hair disorders.

RESULTS

Statistical analysis of the results showed no significant difference in the scores between patients taking finasteride and the control group.

CONCLUSION

Analysis showed no significant difference in sex-related problems with that of patients taking finasteride and age matched controls, suggesting that sex-related issues are not a side effect of finasteride.

摘要

引言

非那雄胺是治疗雄激素性脱发最常用的药物之一。文献中讨论了该药物的性副作用；然而，在实际应用中，几乎没有证据支持这一点。本研究的目的是调查服用1毫克非那雄胺治疗雄激素性脱发的患者的性功能障碍情况。

方法

基于国际勃起功能指数设计了一份问卷，发放给约586名正在接受1毫克非那雄胺治疗、平均治疗时间为16周的雄激素性脱发患者。将这些患者与一个年龄匹配的对照组进行比较，该对照组是因各种与毛发疾病无关的其他皮肤疾病前往皮肤科门诊就诊的患者。

结果

对结果的统计分析显示，服用非那雄胺的患者与对照组的得分没有显著差异。

结论

分析表明，服用非那雄胺的患者与年龄匹配的对照组在性相关问题上没有显著差异，这表明性相关问题不是非那雄胺的副作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57a8/4674453/0f156aa3f92e/13555_2015_84_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57a8/4674453/0f156aa3f92e/13555_2015_84_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57a8/4674453/0f156aa3f92e/13555_2015_84_Fig1_HTML.jpg

相似文献

1
Randomized Questionnaire Based Case-Control Research Study on Evaluation of Sexual Function in Indian Patients Taking Oral Finasteride for Androgenetic Alopecia.基于问卷调查的随机病例对照研究：评估印度口服非那雄胺治疗雄激素性脱发患者的性功能
Dermatol Ther (Heidelb). 2015 Dec;5(4):231-234. doi: 10.1007/s13555-015-0084-3. Epub 2015 Oct 5.
2
Evaluation of sexual function in subjects taking finasteride for the treatment of androgenetic alopecia.非那雄胺治疗雄激素性脱发患者的性功能评估。
J Eur Acad Dermatol Venereol. 2001 Sep;15(5):418-21. doi: 10.1046/j.1468-3083.2001.00315.x.
3
Evaluation of sexual function with an international index of erectile function in subjects taking finasteride for androgenetic alopecia.使用国际勃起功能指数对服用非那雄胺治疗雄激素性脱发的受试者进行性功能评估。
Arch Dermatol. 2004 Jul;140(7):857-8. doi: 10.1001/archderm.140.7.857.
4
Guidelines on the use of finasteride in androgenetic alopecia.非那雄胺治疗雄激素性脱发的指南。
Indian J Dermatol Venereol Leprol. 2016 Mar-Apr;82(2):128-34. doi: 10.4103/0378-6323.177432.
5
Drug Treatment for Androgenetic Alopecia: First Italian Questionnaire Survey on What Dermatologists Think about Finasteride.雄激素性脱发的药物治疗：关于皮肤科医生对非那雄胺看法的首次意大利问卷调查
Dermatol Ther (Heidelb). 2018 Jun;8(2):259-267. doi: 10.1007/s13555-018-0233-6. Epub 2018 Mar 24.
6
Superiority of dutasteride over finasteride in hair regrowth and reversal of miniaturization in men with androgenetic alopecia: A randomized controlled open-label, evaluator-blinded study.度他雄胺在男性雄激素性秃发患者毛发再生及毛囊小型化逆转方面优于非那雄胺：一项随机对照开放标签、评估者盲法研究。
Indian J Dermatol Venereol Leprol. 2017 Jan-Feb;83(1):47-54. doi: 10.4103/0378-6323.188652.
7
Finasteride Topical Delivery Systems for Androgenetic Alopecia.用于雄激素性脱发的非那雄胺局部给药系统。
Curr Drug Deliv. 2018;15(8):1100-1111. doi: 10.2174/1567201815666180124112905.
8
Immunohistochemical evaluation of androgen receptor and nerve structure density in human prepuce from patients with persistent sexual side effects after finasteride use for androgenetic alopecia.非那雄胺用于雄激素性脱发后出现持续性性副作用患者的人包皮中雄激素受体和神经结构密度的免疫组织化学评估
PLoS One. 2014 Jun 24;9(6):e100237. doi: 10.1371/journal.pone.0100237. eCollection 2014.
9
A randomized, active- and placebo-controlled study of the efficacy and safety of different doses of dutasteride versus placebo and finasteride in the treatment of male subjects with androgenetic alopecia.一项多中心、随机、阳性药物对照、双盲临床试验，旨在评估不同剂量度他雄胺治疗男性雄激素性脱发的有效性和安全性。
J Am Acad Dermatol. 2014 Mar;70(3):489-498.e3. doi: 10.1016/j.jaad.2013.10.049. Epub 2014 Jan 9.
10
Efficacy and safety of finasteride therapy for androgenetic alopecia: a systematic review.非那雄胺治疗雄激素性脱发的疗效与安全性：一项系统评价。
Arch Dermatol. 2010 Oct;146(10):1141-50. doi: 10.1001/archdermatol.2010.256.

引用本文的文献

1
Post-finasteride syndrome: An emerging clinical problem.非那雄胺后综合征：一个新出现的临床问题。
Neurobiol Stress. 2019 Dec 26;12:100209. doi: 10.1016/j.ynstr.2019.100209. eCollection 2020 May.
2
Finasteride and Erectile Dysfunction in Patients with Benign Prostatic Hyperplasia or Male Androgenetic Alopecia.非那雄胺与良性前列腺增生或男性雄激素性脱发患者的勃起功能障碍
World J Mens Health. 2019 May;37(2):157-165. doi: 10.5534/wjmh.180029. Epub 2018 Aug 10.
3
Male fertility and skin diseases.男性生育力与皮肤疾病。

本文引用的文献

1
Recent findings with computerized methods for scalp hair growth measurements.
J Investig Dermatol Symp Proc. 2005 Dec;10(3):285-8. doi: 10.1111/j.1087-0024.2005.10125.x.
2
Evaluation of sexual function in subjects taking finasteride for the treatment of androgenetic alopecia.非那雄胺治疗雄激素性脱发患者的性功能评估。
J Eur Acad Dermatol Venereol. 2001 Sep;15(5):418-21. doi: 10.1046/j.1468-3083.2001.00315.x.
3
Improvement in androgenetic alopecia in 53-76-year-old men using oral finasteride.53至76岁男性使用口服非那雄胺治疗雄激素性脱发的疗效
Rev Endocr Metab Disord. 2016 Sep;17(3):353-365. doi: 10.1007/s11154-016-9368-x.
4
Psychosexual disorders and dermatologists.性心理障碍与皮肤科医生。
Indian Dermatol Online J. 2016 May-Jun;7(3):149-58. doi: 10.4103/2229-5178.182349.
Int J Dermatol. 1999 Dec;38(12):928-30. doi: 10.1046/j.1365-4362.1999.00804.x.
4
Clinical dose ranging studies with finasteride, a type 2 5alpha-reductase inhibitor, in men with male pattern hair loss.非那雄胺（一种2型5α-还原酶抑制剂）治疗男性雄激素性脱发的临床剂量范围研究。
J Am Acad Dermatol. 1999 Oct;41(4):555-63.
5
Finasteride in the treatment of men with frontal male pattern hair loss.非那雄胺治疗男性前额型雄激素性脱发
J Am Acad Dermatol. 1999 Jun;40(6 Pt 1):930-7. doi: 10.1016/s0190-9622(99)70081-2.
6
Finasteride in the treatment of men with androgenetic alopecia. Finasteride Male Pattern Hair Loss Study Group.非那雄胺治疗男性雄激素性脱发。非那雄胺男性型脱发研究组。
J Am Acad Dermatol. 1998 Oct;39(4 Pt 1):578-89. doi: 10.1016/s0190-9622(98)70007-6.
7
The international index of erectile function (IIEF): a multidimensional scale for assessment of erectile dysfunction.国际勃起功能指数（IIEF）：一种评估勃起功能障碍的多维量表。
Urology. 1997 Jun;49(6):822-30. doi: 10.1016/s0090-4295(97)00238-0.
8
The comparative histopathology of male-pattern baldness and senescent baldness.
Clin Dermatol. 1988 Oct-Dec;6(4):108-18. doi: 10.1016/0738-081x(88)90074-0.