Sorbellini Elisabetta, Pinto Daniela, Marzani Barbara, Rinaldi Fabio
International Hair Research Foundation (IHRF), Milan, Italy.
Dermatol Ther (Heidelb). 2018 Jun;8(2):259-267. doi: 10.1007/s13555-018-0233-6. Epub 2018 Mar 24.
Treatment with finasteride 1 mg/day represents the therapy of choice for androgenetic alopecia (AGA). We investigated how Italian dermatologists approach use of finasteride for treatment of AGA and common side effects reported by patients.
A tablet-based survey was conducted from February 2017 to January 2018 in Italy to investigating use of 1 mg/day finasteride in the treatment of AGA. Approximately 1153 Italian dermatologists were surveyed about prescription frequency, therapy duration, treatment practices, and side effects eventually reported.
Dermatologists considered treatment with 1 mg/day finasteride to be the most efficacious treatment for AGA, as reflecting by its long-term (5 years) prescription. Data on sexual side effects from our survey are in line with previous scientific evidence, especially regarding loss of libido, erectile dysfunction, and problems with ejaculation, but also in the psychological sphere and regarding physical impairments such as myalgia and loss of muscle tone.
This is the first preliminary observational study on how Italian dermatologists approach use of finasteride to treat AGA. Although side effects have been reported, especially in the sexual sphere, lack of alternative treatments with the same efficacy leads dermatologists to prescribe 1 mg/day finasteride with a tendency to prolong therapy in the long term.
Giuliani S.p.A.
每天服用1毫克非那雄胺是治疗雄激素性脱发（AGA）的首选疗法。我们调查了意大利皮肤科医生如何使用非那雄胺治疗AGA以及患者报告的常见副作用。
2017年2月至2018年1月在意大利进行了一项基于平板电脑的调查，以研究每天1毫克非那雄胺在AGA治疗中的使用情况。约1153名意大利皮肤科医生接受了关于处方频率、治疗持续时间、治疗方法以及最终报告的副作用的调查。
皮肤科医生认为每天1毫克非那雄胺治疗是AGA最有效的治疗方法，这从其长期（5年）处方中得到体现。我们调查中关于性副作用的数据与先前的科学证据一致，特别是关于性欲减退、勃起功能障碍和射精问题，也涉及心理方面以及诸如肌痛和肌肉张力丧失等身体损伤。
这是关于意大利皮肤科医生如何使用非那雄胺治疗AGA的第一项初步观察性研究。尽管已报告有副作用，尤其是在性方面，但由于缺乏具有相同疗效的替代治疗方法，皮肤科医生倾向于长期开具每天1毫克非那雄胺的处方并延长治疗时间。
朱利亚尼股份公司
