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第四脑室以外的菊形团形成型胶质神经元肿瘤:基于病例的最新进展

Rosette-forming glioneuronal tumor outside the fourth ventricle: a case-based update.

作者信息

Beuriat Pierre-Aurelien, Tauziede-Espariat Arnault, Pages Melanie, Varlet Pascalae, Di Rocco Federico

机构信息

Department of Pediatric Neurosurgery, Necker-Enfants Malades Hospital, 149 Rue de Sèvres, 75015, Paris, France.

Department of Pediatric Neurosurgery, Neurological and Neurosurgical Hospital Pierre Wertheimer, 59 Boulevard Pinel, 69677, Lyon Cedex, France.

出版信息

Childs Nerv Syst. 2016 Jan;32(1):65-8. doi: 10.1007/s00381-015-2922-0. Epub 2015 Oct 5.

Abstract

INTRODUCTION

Rosette-forming glioneuronal tumors (RGNTs) that do not involve the fourth ventricle are rare. RGNTs were originally thought to be exclusively localized into the fourth ventricle but were found in various anatomical localizations.

MATERIAL AND METHODS

We review the literature and found 32 cases of this particular RGNT. The outcome was excellent with no mortality reported after surgical treatment. Only two patients had received adjuvant therapy for progression. We added one case of a RGNT located in the cerebellar hemisphere.

CASE AND CONCLUSION

She underwent a subtotal removal with no evidence of progression after. This WHO grade I tumor with a specific biphasic histopathology is of a good oncological outcome after surgical treatment. A long follow-up is needed as recurrence or metastatic progressions exist.

摘要

引言

不涉及第四脑室的菊形团形成型神经胶质神经元肿瘤(RGNTs)很罕见。RGNTs最初被认为仅局限于第四脑室,但后来在各种解剖部位都有发现。

材料与方法

我们回顾文献,发现了32例这种特殊的RGNTs。手术治疗后结果良好,无死亡报告。只有两名患者因病情进展接受了辅助治疗。我们补充了1例位于小脑半球的RGNT病例。

病例与结论

她接受了次全切除,术后无病情进展迹象。这种具有特定双相组织病理学的世界卫生组织I级肿瘤手术治疗后肿瘤学预后良好。由于存在复发或转移进展的情况,需要长期随访。

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