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巴西人群中孕11至13⁺⁶周时静脉导管多普勒测量搏动指数的参考范围。

Reference range for the pulsatility index ductus venosus Doppler measurement between 11 and 13 + 6 weeks of gestation in a Brazilian population.

作者信息

Peixoto Alberto Borges, Caldas Taciana Mara Rodrigues da Cunha, Martins Wellington P, Ferreira Polyana Costa, Nardozza Luciano Marcondes Machado, Costa Fabricio Da Silva, Araujo Júnior Edward

机构信息

a 1Mario Palmério University Hospital - University of Uberaba (UNIUBE) , Uberaba-MG , Brazil .

b 2Radiologic Clinic of Uberaba (CRU) , Uberaba-MG , Brazil .

出版信息

J Matern Fetal Neonatal Med. 2016 Sep;29(17):2738-41. doi: 10.3109/14767058.2015.1103730. Epub 2015 Nov 3.

DOI:10.3109/14767058.2015.1103730
PMID:26438979
Abstract

OBJECTIVE

To establish reference range for the pulsatility index (PI) ductus venosus (DV) Doppler measurement between 11 and 13 + 6 weeks of gestation in a Brazilian population.

METHODS

A retrospective cross-sectional study was performed with 430 singleton pregnancies. The PI DV Doppler measurement was performed as routine during the first trimester screening. DV was identified by color Doppler and the pulsed Doppler gate was placed in the distal portion of the umbilical sinus. When at least three typical DV waveforms were obtained, PI DV was measured manually in one waveform. Polynomial regression was used to obtain the best fit using PI DV Doppler measurement and crown-rump length (CRL) with adjustments by the determination coefficient (R(2)). 5th, 50th and 95th percentiles for the PI DV Doppler measurements at each gestational were determined.

RESULTS

The mean of PI DV Doppler measurement was 1.1 ± 0.2 (range 0.8-3.7). The linear regression was the best fit: PI DV measurement = 1.288-0.0034*CRL (R(2 )= 0.03).

CONCLUSIONS

Reference range for the PI DV Doppler measurement between 11 and 13 + 6 weeks of gestation in a Brazilian population was established.

摘要

目的

建立巴西人群孕11至13⁺⁶周期间静脉导管(DV)搏动指数(PI)多普勒测量的参考范围。

方法

对430例单胎妊娠进行回顾性横断面研究。在孕早期筛查期间,将DV的PI多普勒测量作为常规操作进行。通过彩色多普勒识别DV,并将脉冲多普勒取样容积置于脐窦的远端部分。当获得至少三个典型的DV波形时,在一个波形中手动测量DV的PI。使用多项式回归,通过决定系数(R²)调整,以获得DV的PI多普勒测量值与顶臀长(CRL)之间的最佳拟合。确定每个孕周DV的PI多普勒测量值的第5、第50和第95百分位数。

结果

DV的PI多普勒测量平均值为1.1±0.2(范围0.8 - 3.7)。线性回归拟合最佳:DV的PI测量值 = 1.288 - 0.0034×CRL(R² = 0.03)。

结论

建立了巴西人群孕11至13⁺⁶周期间DV的PI多普勒测量的参考范围。

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