Bozdag Gurkan
Department of Obstetrics & Gynaecology, School of Medicine, Hacettepe University, Ankara, Turkey.
Womens Health (Lond). 2015 Aug;11(5):693-9. doi: 10.2217/whe.15.56. Epub 2015 Oct 6.
While the incidence of endometriosis is up to 40-60% in women with severe dysmenorrhea/chronic pelvic pain, patients with subfertility carries a risk up to 20-30%. In symptomatic patients, although medical therapy is preferred in women with endometriosis, surgery might be needed in nonresponders or patients with an endometrioma. Following the surgery, recurrence of the disease and/or symptoms might be still noticed which will progressively increase as times goes by. Nevertheless, some risk factors have been identified for the risk of recurrence that decreases the success of the procedure. Those risk factors might be classified as patient-disease related and surgery-associated variables. Herein, we will address about the management of endometriosis regarding the risk factors for relapse, mechanisms of recurrence and potential biomarkers to predict the event.
虽然在患有严重痛经/慢性盆腔疼痛的女性中，子宫内膜异位症的发病率高达40%-60%，但在不孕患者中，其风险高达20%-30%。在有症状的患者中，虽然子宫内膜异位症女性首选药物治疗，但无反应者或患有子宫内膜瘤的患者可能需要手术治疗。手术后，仍可能会注意到疾病和/或症状的复发，并且随着时间的推移会逐渐增加。然而，已经确定了一些复发风险因素，这些因素会降低手术的成功率。这些风险因素可分为与患者疾病相关的变量和与手术相关的变量。在此，我们将探讨子宫内膜异位症复发风险因素、复发机制以及预测该事件的潜在生物标志物方面的管理问题。
