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子宫内膜异位症综合护理:一种治疗盆腔疼痛和子宫内膜异位症的现代多模式方法。

Comprehensive endometriosis care: a modern multimodal approach for the treatment of pelvic pain and endometriosis.

作者信息

Mick Ido, Freger Shay M, van Keizerswaard Jolanda, Gholiof Mahsa, Leonardi Mathew

机构信息

Department of Obstetrics and Gynecology, McMaster University, Hamilton, ON, Canada.

Department of Obstetrics and Gynecology, McMaster University, 1280 Main Street West, Hamilton, ON L8N 3Z5, Canada.

出版信息

Ther Adv Reprod Health. 2024 Sep 23;18:26334941241277759. doi: 10.1177/26334941241277759. eCollection 2024 Jan-Dec.

DOI:10.1177/26334941241277759
PMID:39376635
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11457249/
Abstract

Endometriosis is a prevalent gynecological disease, leading to chronic pain and inflammation, affecting 1 in 10 individuals presumed female at birth. The diagnostic journey is often arduous, marked by neglect of the right diagnosis and prolonged wait times, significantly compromising the quality of life among those affected. This review provides a nuanced exploration of endometriosis-associated pain management, encompassing medical, surgical, and holistic approaches, all guided by accurate and refined diagnostics. Our paramount goal is to empower physicians as key figures in confronting this intricate challenge with a patient-centric approach, ultimately aiming to improve treatment and quality of life. Acknowledging each patient's unique needs, we emphasize the importance of tailoring a spectrum of options informed by current literature and insights gleaned from our experience in a high-volume tertiary endometriosis center. It is imperative to recognize endometriosis as a complex and chronic disease, often occurring with co-morbid conditions and nuanced complexities, necessitating a long-term personalized multimodal approach for each case. In addition, incorporating principles such as patient autonomy, profound respect for diverse experiences, and practical education on treatment choices is pivotal in enhancing treatment outcomes and overall patient satisfaction.

摘要

子宫内膜异位症是一种常见的妇科疾病,会导致慢性疼痛和炎症,在每10名出生时被认定为女性的个体中就有1人受其影响。诊断过程往往很艰难,存在误诊和等待时间过长的问题,严重影响了患者的生活质量。本综述对子宫内膜异位症相关的疼痛管理进行了细致入微的探讨,涵盖了药物、手术和整体治疗方法,所有这些都以准确和精细的诊断为指导。我们的首要目标是让医生成为以患者为中心应对这一复杂挑战的关键人物,最终目的是改善治疗效果和生活质量。认识到每位患者的独特需求,我们强调根据当前文献以及从我们在一家大型三级子宫内膜异位症中心的经验中获得的见解,量身定制一系列治疗方案的重要性。必须认识到子宫内膜异位症是一种复杂的慢性疾病,常伴有合并症和细微的复杂性,因此每个病例都需要长期的个性化多模式治疗方法。此外,纳入患者自主权、对不同经历的深刻尊重以及关于治疗选择的实用教育等原则,对于提高治疗效果和患者总体满意度至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ecb3/11457249/42d5f6144916/10.1177_26334941241277759-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ecb3/11457249/42d5f6144916/10.1177_26334941241277759-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ecb3/11457249/42d5f6144916/10.1177_26334941241277759-fig1.jpg

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本文引用的文献

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Society of Radiologists in Ultrasound Consensus on Routine Pelvic US for Endometriosis.超声放射学会关于子宫内膜异位症常规盆腔超声检查的共识。
Radiology. 2024 Apr;311(1):e232191. doi: 10.1148/radiol.232191.
2
Guideline No. 449: Diagnosis and Impact of Endometriosis - A Canadian Guideline.第449号指南:子宫内膜异位症的诊断与影响——加拿大指南。
J Obstet Gynaecol Can. 2024 May;46(5):102450. doi: 10.1016/j.jogc.2024.102450. Epub 2024 Mar 28.
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Two-year efficacy and safety of relugolix combination therapy in women with endometriosis-associated pain: SPIRIT open-label extension study.
地诺孕素与复方口服避孕药:一项关于疗效和副作用的系统评价与荟萃分析,以指导循证指南制定
Acta Obstet Gynecol Scand. 2025 Aug;104(8):1424-1432. doi: 10.1111/aogs.15145. Epub 2025 May 1.
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Analysis of the Biopsychosocial Impacts Associated with Endometriosis to Improve Patient Care.分析与子宫内膜异位症相关的生物心理社会影响以改善患者护理。
J Clin Med. 2025 Mar 21;14(7):2158. doi: 10.3390/jcm14072158.
在患有子宫内膜异位症相关疼痛的女性中,瑞戈非尼联合治疗的两年疗效和安全性:SPIRIT 开放标签扩展研究。
Hum Reprod. 2024 Mar 1;39(3):526-537. doi: 10.1093/humrep/dead263.
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Noninvasive diagnostic imaging for endometriosis part 1: a systematic review of recent developments in ultrasound, combination imaging, and artificial intelligence.子宫内膜异位症的无创性诊断成像 第 1 部分:超声、组合成像和人工智能最新进展的系统评价。
Fertil Steril. 2024 Feb;121(2):164-188. doi: 10.1016/j.fertnstert.2023.12.008. Epub 2023 Dec 14.
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Symptoms of mental disorders and oral contraception use: A systematic review and meta-analysis.精神障碍症状与口服避孕药使用:系统评价与荟萃分析。
Front Neuroendocrinol. 2024 Jan;72:101111. doi: 10.1016/j.yfrne.2023.101111. Epub 2023 Nov 14.
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The impact of endometriosis on dietary choices and activities of everyday life: a cross-sectional study.子宫内膜异位症对饮食选择及日常生活活动的影响:一项横断面研究。
Front Nutr. 2023 Sep 22;10:1273976. doi: 10.3389/fnut.2023.1273976. eCollection 2023.
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Experiences of communication in women with endometriosis: perceived validation and invalidation in different contexts, and associations with health-related quality of life.子宫内膜异位症女性的沟通体验:不同情境下的感知验证和否定,以及与健康相关生活质量的关联。
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Evaluation of the effect of previous endometriosis surgery on clinical and surgical outcomes of subsequent endometriosis surgery.评估既往子宫内膜异位症手术对后续子宫内膜异位症手术临床和手术结局的影响。
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