共识文件：小脑发育
Consensus Paper: Cerebellar Development.
作者信息
Leto Ketty, Arancillo Marife, Becker Esther B E, Buffo Annalisa, Chiang Chin, Ding Baojin, Dobyns William B, Dusart Isabelle, Haldipur Parthiv, Hatten Mary E, Hoshino Mikio, Joyner Alexandra L, Kano Masanobu, Kilpatrick Daniel L, Koibuchi Noriyuki, Marino Silvia, Martinez Salvador, Millen Kathleen J, Millner Thomas O, Miyata Takaki, Parmigiani Elena, Schilling Karl, Sekerková Gabriella, Sillitoe Roy V, Sotelo Constantino, Uesaka Naofumi, Wefers Annika, Wingate Richard J T, Hawkes Richard
机构信息
Department of Neuroscience Rita Levi Montalcini, University of Turin, via Cherasco 15, 10026, Turin, Italy.
Neuroscience Institute Cavalieri-Ottolenghi, University of Turin, Regione Gonzole 10, 10043, Orbassano, Torino, Italy.
出版信息
Cerebellum. 2016 Dec;15(6):789-828. doi: 10.1007/s12311-015-0724-2.
The development of the mammalian cerebellum is orchestrated by both cell-autonomous programs and inductive environmental influences. Here, we describe the main processes of cerebellar ontogenesis, highlighting the neurogenic strategies used by developing progenitors, the genetic programs involved in cell fate specification, the progressive changes of structural organization, and some of the better-known abnormalities associated with developmental disorders of the cerebellum.
哺乳动物小脑的发育是由细胞自主程序和诱导性环境影响共同调控的。在此，我们描述小脑个体发生的主要过程，重点介绍发育中的祖细胞所采用的神经发生策略、细胞命运特化所涉及的遗传程序、结构组织的渐进性变化，以及一些与小脑发育障碍相关的较为知名的异常情况。
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