Miyashiro Denis, Sanches Jose A
Department of Dermatology, University of São Paulo Medical School, São Paulo, Brazil -
G Ital Dermatol Venereol. 2016 Feb;151(1):55-76. Epub 2015 Oct 6.
Paraneoplastic disorders are manifestations of internal malignancies without the direct action of the tumor. Its pathogenesis involves production of substances that interfere with cellular activity of distant tissues. Paraneoplasias may be the first sign of cancer, and clinicians should be familiarized with its manifestations in order to perform an early diagnosis of the underlying neoplasm. The aim of this review was to describe most common paraneoplastic skin diseases.
副肿瘤性疾病是体内恶性肿瘤的表现，而非肿瘤的直接作用所致。其发病机制涉及产生干扰远处组织细胞活性的物质。副肿瘤综合征可能是癌症的首发症状，临床医生应熟悉其表现，以便对潜在肿瘤进行早期诊断。本综述的目的是描述最常见的副肿瘤性皮肤病。
