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推动药物基因组学成为精准医学的一部分:方式、地点和对象?

Advancing Pharmacogenomics as a Component of Precision Medicine: How, Where, and Who?

作者信息

Johnson J A, Weitzel K W

机构信息

Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics, University of Florida, Gainesville, Florida, USA.

出版信息

Clin Pharmacol Ther. 2016 Feb;99(2):154-6. doi: 10.1002/cpt.273. Epub 2015 Nov 9.

Abstract

Pharmacogenomics is an important element of precision medicine. Advances in pharmacogenomics implementation have been made but significant barriers remain, including evidence, reimbursement, and clinician knowledge, among others. Widespread adoption of pharmacogenomics requires overcoming these barriers, a clinician champion group, which we propose will be pharmacists, and an easily accessible setting, which may be the community pharmacy. Whatever the path, it must be evidence-driven and pharmacogenomics must improve drug-related outcomes to become a standard of care.

摘要

药物基因组学是精准医学的一个重要组成部分。虽然在药物基因组学的实施方面已经取得了进展,但仍然存在重大障碍,包括证据、报销和临床医生知识等。药物基因组学的广泛应用需要克服这些障碍、一个临床医生支持群体(我们建议由药剂师组成)以及一个易于进入的场所(可能是社区药房)。无论采取何种途径,都必须以证据为导向,并且药物基因组学必须改善与药物相关的结果才能成为一种护理标准。

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