伴有视乳头旁脉络膜新生血管膜的视盘玻璃疣所致的假性葡萄膜黑色素瘤
PSEUDO UVEAL MELANOMA CAUSED BY OPTIC DISK DRUSEN WITH JUXTAPAPILLARY CHOROIDAL NEOVASCULAR MEMBRANE.
作者信息
Marr Brian, Reinherz Benjamin, Belinsky Irina, Saffra Norman A
机构信息
*Ophthalmic Oncology Service, Memorial Sloan-Kettering Cancer Center, New York, New York; †Department of Ophthalmology, St. John's Episcopal Hospital, Far Rockaway, New York; and ‡Department of Ophthalmology, Maimonides Medical Center, Brooklyn, New York.
出版信息
Retin Cases Brief Rep. 2016 Spring;10(2):168-70. doi: 10.1097/ICB.0000000000000218.
PURPOSE
To describe two cases of choroidal hemorrhage caused by optic disk drusen-induced choroidal neovascularization simulating uveal melanoma.
METHODS
Observational case reports of two patients and brief review of the literature.
RESULTS
Two patients were referred with pigmented juxtapapillary lesions concerning for choroidal melanoma. Multimodal imaging revealed the presence of optic disk drusen with overlying choroidal neovascular membranes and peripapillary choroidal hemorrhage. Both patients were treated with antivascular endothelial growth factor and the lesions resolved.
CONCLUSION
In the setting of diagnostic uncertainty, careful multimodal imaging can assist in distinguishing between malignant choroidal melanoma and a benign simulating lesion. Optic disk drusen with associated neovascularization and hemorrhage should be included in the list of pseudomelanomas.
目的
描述两例由视盘玻璃疣诱导的脉络膜新生血管形成导致脉络膜出血的病例，其表现类似于葡萄膜黑色素瘤。
方法
对两名患者的观察性病例报告及文献简要回顾。
结果
两名患者因疑似脉络膜黑色素瘤的色素性视乳头旁病变前来就诊。多模态成像显示存在视盘玻璃疣，其上覆盖有脉络膜新生血管膜及视乳头周围脉络膜出血。两名患者均接受了抗血管内皮生长因子治疗，病变得以消退。
结论
在诊断存在不确定性的情况下，仔细的多模态成像有助于区分恶性脉络膜黑色素瘤和良性模拟病变。伴有新生血管形成和出血的视盘玻璃疣应列入假黑色素瘤的范畴。
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