Herman B M, Charlap S, Frishman W H
Department of Medicine, Maimonides Medical Center, Brooklyn, New York.
Med Clin North Am. 1989 Mar;73(2):361-71. doi: 10.1016/s0025-7125(16)30677-0.
An important role for nitrates in the treatment of patients with congestive heart failure has been demonstrated. By dilating the venous and arterial vasculature, they improve hemodynamics as well as exercise tolerance. Attenuation of nitrate action that occurs with chronic therapy can be minimized by following certain treatment strategies.
硝酸盐在充血性心力衰竭患者治疗中的重要作用已得到证实。通过扩张静脉和动脉血管系统,它们可改善血流动力学以及运动耐量。遵循某些治疗策略可将长期治疗时发生的硝酸盐作用减弱降至最低程度。