Verheij C, Louwerse A, van der Ende J, Eussen M L J M, Van Gool A R, Verheij F, Verhulst F C, Greaves-Lord K
Department of Child and Adolescent Psychiatry/Psychology, Erasmus Medical Center/Sophia Children's Hospital, Dr. Molewaterplein 60, 3015 GJ, Rotterdam, The Netherlands.
Yulius Academy, Yulius, Organisation of Mental Health, Dordrecht, The Netherlands.
J Autism Dev Disord. 2015 Dec;45(12):3939-48. doi: 10.1007/s10803-015-2592-5.
The current study was a 7-year follow-up of 74 6-12 year old children with Pervasive Developmental Disorder-Not Otherwise Specified. We examined the rates and 7 year stability of comorbid psychiatric diagnoses as ascertained with the Diagnostic Interview Schedule for Children: Parent version at ages 6-12 and again at ages 12-20. Also, we examined childhood factors that predicted the stability of comorbid psychiatric disorders. The rate of comorbid psychiatric disorders dropped significantly from childhood (81 %) to adolescence (61 %). Higher levels of parent reported stereotyped behaviors and reduced social interest in childhood significantly predicted the stability of psychiatric comorbidity. Re-evaluation of psychiatric comorbidity should be considered in clinical practice, since several individuals shifted in comorbid diagnoses.
本研究对74名6 - 12岁未特定的广泛性发育障碍儿童进行了为期7年的随访。我们通过儿童诊断访谈量表：家长版，分别在6 - 12岁和12 - 20岁时，检查了共病精神疾病诊断的发生率及7年稳定性。此外，我们还研究了预测共病精神疾病稳定性的儿童期因素。共病精神疾病的发生率从儿童期（81%）到青春期（61%）显著下降。家长报告的儿童期刻板行为水平较高和社交兴趣降低显著预测了精神共病的稳定性。由于一些个体的共病诊断发生了变化，临床实践中应考虑对精神共病进行重新评估。
