Gupta Vikas, Mah Xian-Jun, Garcia Maria Carmela, Antonypillai Christina, van der Poorten David
Vikas Gupta, Xian-Jun Mah, Maria Carmela Garcia, Christina Antonypillai, David van der Poorten, Department of Gastroenterology and Hepatology, Division of Medicine, University of Sydney at Westmead Hospital, Westmead, New South Wales, NSW 2145, Australia.
World J Gastroenterol. 2015 Oct 7;21(37):10621-35. doi: 10.3748/wjg.v21.i37.10621.
Rates of non-alcoholic fatty liver disease (NAFLD) are increasing worldwide in tandem with the metabolic syndrome, with the progressive form of disease, non-alcoholic steatohepatitis (NASH) likely to become the most common cause of end stage liver disease in the not too distant future. Lifestyle modification and weight loss remain the main focus of management in NAFLD and NASH, however, there has been growing interest in the benefit of specific foods and dietary components on disease progression, with some foods showing protective properties. This article provides an overview of the foods that show the most promise and their potential benefits in NAFLD/NASH, specifically; oily fish/ fish oil, coffee, nuts, tea, red wine, avocado and olive oil. Furthermore, it summarises results from animal and human trials and highlights potential areas for future research.
非酒精性脂肪性肝病(NAFLD)的发病率在全球范围内正随着代谢综合征的增加而上升,这种疾病的进展形式——非酒精性脂肪性肝炎(NASH)很可能在不久的将来成为终末期肝病的最常见原因。生活方式的改变和体重减轻仍然是NAFLD和NASH管理的主要重点,然而,人们越来越关注特定食物和饮食成分对疾病进展的益处,一些食物显示出保护作用。本文概述了在NAFLD/NASH中最具前景的食物及其潜在益处,具体包括:油性鱼类/鱼油、咖啡、坚果、茶、红酒、鳄梨和橄榄油。此外,它总结了动物和人体试验的结果,并突出了未来研究的潜在领域。