Blair Robert J R
Section of Affective Cognitive Neuroscience, National Institute of Mental Health, National Institutes of Health , Department of Health and Human Services, Bethesda, Maryland.
J Child Adolesc Psychopharmacol. 2016 Feb;26(1):4-9. doi: 10.1089/cap.2015.0088. Epub 2015 Oct 14.
This selective review provides a model of the neurobiology of impulsive aggression from a cognitive neuroscience perspective. It is argued that prototypical cases of impulsive aggression, those associated with anger, involve the recruitment of the acute threat response system structures; that is, the amygdala, hypothalamus, and periaqueductal gray. It is argued that whether the recruitment of these structures results in impulsive aggression or not reflects the functional roles of ventromedial frontal cortex and dorsomedial frontal and anterior insula cortex in response selection. It is also argued that impulsive aggression may occur because of impaired decision making. The aggression may not be accompanied by anger, but it will reflect disrupted evaluation of the rewards/benefits of the action.
这篇选择性综述从认知神经科学的角度提供了一个冲动性攻击行为的神经生物学模型。有人认为，冲动性攻击行为的典型案例，即那些与愤怒相关的案例，涉及到急性威胁反应系统结构的激活，也就是杏仁核、下丘脑和导水管周围灰质。有人认为，这些结构的激活是否会导致冲动性攻击行为，反映了腹内侧前额叶皮层以及背内侧前额叶和前脑岛皮层在反应选择中的功能作用。还有人认为，冲动性攻击行为可能是由于决策受损而发生的。这种攻击行为可能不会伴有愤怒，但它会反映出对该行为的奖励/益处的评估受到了干扰。
