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Lower urinary tract symptoms, benign prostatic hyperplasia/benign prostatic enlargement and erectile dysfunction: are these conditions related to vascular dysfunction?下尿路症状、良性前列腺增生/良性前列腺肿大与勃起功能障碍:这些病症与血管功能障碍有关吗?
Int J Urol. 2014 Sep;21(9):856-64. doi: 10.1111/iju.12501. Epub 2014 Jun 15.
2
Carotid artery intima-media thickness and erectile dysfunction in patients with metabolic syndrome.代谢综合征患者的颈动脉内膜中层厚度与勃起功能障碍
Med Sci Monit. 2014 May 29;20:884-8. doi: 10.12659/MSM.889771.
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Treatment of LUTS secondary to BPH while preserving sexual function: randomized controlled study of prostatic urethral lift.治疗良性前列腺增生症引起的下尿路症状同时保留性功能:前列腺尿道提升的随机对照研究。
J Sex Med. 2014 Jan;11(1):279-87. doi: 10.1111/jsm.12333. Epub 2013 Sep 30.
4
Efficacy and safety of the coadministration of tadalafil once daily with finasteride for 6 months in men with lower urinary tract symptoms and prostatic enlargement secondary to benign prostatic hyperplasia.每日一次他达拉非联合非那雄胺治疗良性前列腺增生所致下尿路症状和前列腺增生的 6 个月疗效和安全性。
J Urol. 2014 Mar;191(3):727-33. doi: 10.1016/j.juro.2013.09.059. Epub 2013 Oct 2.
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PDE5 inhibitors blunt inflammation in human BPH: a potential mechanism of action for PDE5 inhibitors in LUTS.PDE5 抑制剂可抑制人前列腺增生的炎症:PDE5 抑制剂在 LUTS 中作用机制的一种潜在假说。
Prostate. 2013 Sep;73(13):1391-402. doi: 10.1002/pros.22686. Epub 2013 Jun 13.
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Silodosin versus naftopidil for the treatment of benign prostatic hyperplasia: a multicenter randomized trial.西洛多辛与萘哌地尔治疗良性前列腺增生症的多中心随机试验。
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Effect of selective alpha-blocker tamsulosin on erectile function in patients with lower urinary tract symptoms due to benign prostatic hyperplasia.选择性α-受体阻滞剂坦索罗辛对良性前列腺增生所致下尿路症状患者勃起功能的影响。
Urology. 2013 Jul;82(1):130-5. doi: 10.1016/j.urology.2013.03.026. Epub 2013 May 25.
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Age-related changes in general and sexual health in middle-aged and older men: results from the European Male Ageing Study (EMAS).中老年男性一般健康和性健康的年龄相关性变化:来自欧洲男性衰老研究(EMAS)的结果。
J Sex Med. 2010 Apr;7(4 Pt 1):1362-80. doi: 10.1111/j.1743-6109.2009.01601.x. Epub 2009 Nov 19.
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Correlation between Lower Urinary Tract Symptoms (LUTS) and sexual function in benign prostatic hyperplasia: impact of treatment of LUTS on sexual function.下尿路症状(LUTS)与良性前列腺增生症患者性功能的相关性:LUTS 治疗对性功能的影响。
J Sex Med. 2009 Aug;6(8):2299-304. doi: 10.1111/j.1743-6109.2009.01324.x. Epub 2009 Jun 2.
10
Erectile dysfunction and lower urinary tract symptoms secondary to BPH.良性前列腺增生继发的勃起功能障碍和下尿路症状
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50岁及以上男性的下尿路症状、勃起功能障碍及其相关性:中国北京的一项横断面调查

Lower urinary tract symptoms, erectile dysfunction, and their correlation in men aged 50 years and above: a cross-sectional survey in Beijing, China.

作者信息

Song Jian, Shao Qiang, Tian Ye, Chen Shan

机构信息

Department of Urology, Beijing Friendship Hospital, Capital Medical Universty, Beijing, China (mainland).

出版信息

Med Sci Monit. 2014 Dec 28;20:2806-10. doi: 10.12659/MSM.891180.

DOI:10.12659/MSM.891180
PMID:25543209
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4285920/
Abstract

BACKGROUND

The aim of this study was to investigate the correlation between incidence of lower urinary tract symptoms and erectile dysfunction in men aged ≥50 years.

MATERIAL AND METHODS

A cross-sectional study was performed in 1644 men aged >50 years in Beijing. The International Index of Erectile Function (IIEF)-5 and International Prostate Symptom Score were recorded for each patient. Pearson's chi-square test and Spearman correlation coefficients were used to analyze the International Prostate Symptom Scores and lower urinary tract symptoms, and their correlations with erectile dysfunction.

RESULTS

The incidence rates of erectile dysfunction among men with mild, moderate, and severe lower urinary tract symptoms were 85.7, 93.7, and 97.9%, respectively. Interestingly, the total IIEF-5 score significantly correlated with the total International Prostate Symptom Score (r=-0.335; P<0.01), obstructive symptoms (r=-0.276; P<0.01), and irritative symptoms (r=-0.326; P<0.01). The correlation between the severity of lower urinary tract symptoms and that of erectile dysfunction was consistently maintained (r=0.304; P<0.01). Age significantly correlated with International Prostate Symptom Score (r=0.388; P<0.01), lower urinary tract symptoms severity (r=0.457; P<0.01), total IIEF-5 score (r=-0.533; P<0.01), and erectile dysfunction severity (r=0.529; P<0.01).

CONCLUSIONS

The incidence of lower urinary tract symptoms and erectile dysfunction in aging men increase with age, and the severity of erectile dysfunction is positively correlated with the severity of lower urinary tract symptoms.

摘要

背景

本研究旨在调查50岁及以上男性下尿路症状发生率与勃起功能障碍之间的相关性。

材料与方法

对北京1644名50岁以上男性进行了一项横断面研究。记录每位患者的国际勃起功能指数(IIEF)-5和国际前列腺症状评分。采用Pearson卡方检验和Spearman相关系数分析国际前列腺症状评分与下尿路症状及其与勃起功能障碍的相关性。

结果

轻度、中度和重度下尿路症状男性的勃起功能障碍发生率分别为85.7%、93.7%和97.9%。有趣的是,IIEF-5总分与国际前列腺症状总分(r=-0.335;P<0.01)、梗阻性症状(r=-0.276;P<0.01)和刺激性症状(r=-0.326;P<0.01)显著相关。下尿路症状严重程度与勃起功能障碍严重程度之间的相关性持续存在(r=0.304;P<0.01)。年龄与国际前列腺症状评分(r=0.388;P<0.01)、下尿路症状严重程度(r=0.457;P<0.01)、IIEF-5总分(r=-0.533;P<0.01)和勃起功能障碍严重程度(r=0.529;P<0.01)显著相关。

结论

老年男性下尿路症状和勃起功能障碍的发生率随年龄增加而升高,勃起功能障碍的严重程度与下尿路症状的严重程度呈正相关。