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韩国国家健康与营养检查调查(KNHANES)中主动吸烟、接触二手烟及其与抑郁症状的关系。

Active smoking and exposure to secondhand smoke and their relationship to depressive symptoms in the Korea national health and nutrition examination survey (KNHANES).

作者信息

Jung Sun Jae, Shin Aesun, Kang Daehee

机构信息

Department of Biomedical Science, Seoul National University College of Medicine, Seoul, South Korea.

Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, South Korea.

出版信息

BMC Public Health. 2015 Oct 14;15:1053. doi: 10.1186/s12889-015-2402-1.

Abstract

BACKGROUND

The relationship between tobacco smoking, including secondhand smoking, and depression has been assessed. The purpose of this study was to evaluate the association between secondhand smoking among current, former and never smokers and depressive symptoms. For secondhand smoking, gender differences and sources of exposure were examined.

METHODS

Data from 34,693 participants from the fourth and fifth Korean Health and Nutritional Examination Survey (2007-2012) were analyzed in 2014. Self-reported exposure to active (current, former or never) and secondhand smoking and depressive symptoms experienced during the past year were analyzed using logistic regression. The dose-response relationship between duration of secondhand smoke exposure and depression was assessed with stratification by gender and sources of exposure (at home only, at the workplace only or both).

RESULTS

Regardless of their smoking status, all women who had secondhand smoke exposure at home reported more depressive symptoms than non-smoking women without any exposure to secondhand cigarette smoking (OR 1.43, 95 % CI 1.04-1.96 for current smokers; OR 2.32, 95 % CI 1.04-5.16 for former smokers; OR 1.25, 95 % CI 1.08-1.43 for never smokers). There was also a significant dose-response pattern (p-trend <0.001) for the duration of secondhand smoke exposure at home among women. No significant association was found between smoking and depressive symptoms in men.

CONCLUSIONS

There was a significant association between secondhand smoke exposure at home and depressive symptoms in women. Secondhand smoke exposure at home was associated with depressive symptoms in a dose-response manner.

摘要

背景

已对吸烟(包括二手烟)与抑郁症之间的关系进行了评估。本研究的目的是评估当前吸烟者、既往吸烟者和从不吸烟者中的二手烟暴露与抑郁症状之间的关联。对于二手烟暴露,研究了性别差异和暴露源。

方法

2014年对来自韩国第四次和第五次健康与营养检查调查(2007 - 2012年)的34693名参与者的数据进行了分析。使用逻辑回归分析自我报告的主动吸烟(当前、既往或从不)和二手烟暴露情况以及过去一年中经历的抑郁症状。通过按性别和暴露源(仅在家中、仅在工作场所或两者皆有)分层,评估二手烟暴露持续时间与抑郁症之间的剂量反应关系。

结果

无论吸烟状况如何,所有在家中暴露于二手烟的女性报告的抑郁症状均多于未接触二手烟的非吸烟女性(当前吸烟者的比值比为1.43,95%置信区间为1.04 - 1.96;既往吸烟者的比值比为2.32,95%置信区间为1.04 - 5.16;从不吸烟者的比值比为1.25,95%置信区间为1.08 - 1.43)。在家中二手烟暴露持续时间方面,女性也存在显著的剂量反应模式(p趋势<0.001)。未发现男性吸烟与抑郁症状之间存在显著关联。

结论

在家中暴露于二手烟与女性的抑郁症状之间存在显著关联。在家中暴露于二手烟与抑郁症状呈剂量反应关系。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/29c0/4606499/3c48071ae2a7/12889_2015_2402_Fig1_HTML.jpg

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