Bonaque-González Sergio, Ríos Susana, Amigó Alfredo, López-Gil Norberto
J Refract Surg. 2015 Oct;31(10):651-7. doi: 10.3928/1081597X-20150922-01.
To evaluate visual quality when changing the intraocular orientation of the Lentis Mplus LS-312MF nonrotational symmetric +3.00 diopters aspheric multifocal intraocular lens ([IOL] Oculentis GmbH, Berlin, Germany) in normal eyes.
An artificial eye was used to measure the in vitro wavefront of the IOL. The corneal topography of 20 healthy patients was obtained. For each eye, a computational analysis simulated the implantation of the IOL. The modulation transfer function (MTF) and an image quality parameter (visually modulated transfer function [VSMTF] metric) were calculated for a 5.0-mm pupil and for three conditions: distance, intermediate, and near vision. The procedure was repeated for each eye after a rotation of the IOL with respect to the cornea from 0° to 360° in 1° steps.
Statistical analysis showed significant differences in mean VSMTF values between orientations for distance vision. Optimal orientation of the IOL (different for each eye) showed a mean improvement of 58% ± 19% (range: 20% to 121%) in VSMTF values with respect to the worst possible orientation. For these orientations, intermediate and near vision quality were statistically indistinguishable. The MTFs were different between orientations, showing a mean difference of approximately 5 cycles per degree in the maximum spatial frequencies that can be transferred between the best and the worst orientations for distance vision.
The results suggest that implantation of this nonrotational symmetric IOL should improve visual outcomes if it is oriented to coincide with a customized meridian. A simple, practical method is proposed to find an approximation to the angle that an Mplus IOL should be inserted.
评估在正常眼中改变Lentis Mplus LS - 312MF非旋转对称+3.00屈光度非球面多焦点人工晶状体(IOL,德国柏林Oculentis GmbH公司)的眼内方位时的视觉质量。
使用人工眼测量IOL的体外波前。获取20名健康患者的角膜地形图。对于每只眼睛,通过计算分析模拟IOL的植入。针对5.0毫米瞳孔以及三种情况(远视力、中视力和近视力)计算调制传递函数(MTF)和图像质量参数(视觉调制传递函数[VSMTF]指标)。在IOL相对于角膜以1°步长从0°旋转至360°后,对每只眼睛重复该过程。
统计分析表明,远视力不同方位之间的平均VSMTF值存在显著差异。IOL的最佳方位(每只眼睛不同)相对于最差方位,VSMTF值平均提高了58%±19%(范围:20%至121%)。对于这些方位,中视力和近视力质量在统计学上无显著差异。不同方位之间的MTF不同,在远视力最佳和最差方位之间可传递的最大空间频率上,平均差异约为每度5周。
结果表明,如果将这种非旋转对称IOL定向为与定制子午线重合,则植入后应能改善视觉效果。提出了一种简单实用的方法来找到Mplus IOL应插入角度的近似值。