链霉菌属菌株22-4产生的环（L-脯氨酸-L-酪氨酸）和环（D-脯氨酸-L-酪氨酸）对植物病原菌的抗菌活性。
Antibacterial activity of cyclo(L-Pro-L-Tyr) and cyclo(D-Pro-L-Tyr) from Streptomyces sp. strain 22-4 against phytopathogenic bacteria.
作者信息
Wattana-Amorn Pakorn, Charoenwongsa Waranya, Williams Christopher, Crump Matthew P, Apichaisataienchote Busaya
机构信息
a Faculty of Science, Department of Chemistry, Center of Excellence for Innovation in Chemistry and Special Research Unit for Advanced Magnetic Resonance , Kasetsart University , Bangkok , Thailand.
b School of Chemistry , University of Bristol , Bristol , United Kingdom.
出版信息
Nat Prod Res. 2016 Sep;30(17):1980-3. doi: 10.1080/14786419.2015.1095747. Epub 2015 Oct 15.
Two bioactive cyclic dipeptides, cyclo(L-Pro-L-Tyr) and cyclo(D-Pro-L-Tyr), were isolated from the culture broth of Streptomyces sp. strain 22-4 and tested against three economically important plant pathogens, Xanthomonas axonopodis pv. citri, Ralstonia solanacearum and Clavibacter michiganensis. Both cyclic dipeptides were active against X. axonopodis pv. citri and R. Solanacearum with MIC of 31.25 μg/mL. No activity could be observed against C. michiganensis.
从链霉菌属菌株22-4的培养液中分离出两种生物活性环二肽，环（L-脯氨酸-L-酪氨酸）和环（D-脯氨酸-L-酪氨酸），并针对三种具有重要经济意义的植物病原体进行了测试，即柑桔溃疡病菌、青枯雷尔氏菌和密执安棒形杆菌。两种环二肽对柑桔溃疡病菌和青枯雷尔氏菌均有活性，最低抑菌浓度为31.25μg/mL。未观察到对密执安棒形杆菌有活性。
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