Department of Medicine (Dermatology), University of Toronto, Toronto, Ontario, Canada.
Department of Dermatology, University of Miami, Miami, Florida; Department of Cutaneous Surgery, University of Miami, Miami, Florida.
J Am Acad Dermatol. 2015 Nov;73(5 Suppl 1):S55-61. doi: 10.1016/j.jaad.2015.07.048.
Hidradenitis suppurativa (HS) is a chronic, recurrent, debilitating disease predominantly involving apocrine gland-bearing skin. The folliculoinfundibular dysfunction and an aberrant cutaneous immune response to commensal bacteria are recognized as potential contributors. Topical antibiotics, such as clindamycin, and keratolytic agents have been used in the management of early stages of HS. Proper wound care is a key part of management, particularly in patients with advanced HS. The evidence for the optimal topical therapy or optimal local wound care is limited. As such, a multidisciplinary approach is necessary to address all aspects of HS, including topical therapy, systemic therapy, and proper wound care. The focus of this paper is to review the evidence for the topical management and local wound care strategies in patients with HS.
化脓性汗腺炎（HS）是一种慢性、复发性、使人虚弱的疾病，主要涉及顶泌汗腺皮肤。毛囊漏斗功能障碍和对共生细菌的异常皮肤免疫反应被认为是潜在的致病因素。局部抗生素，如克林霉素和角质松解剂，已被用于 HS 的早期治疗。适当的伤口护理是管理的关键部分，特别是在患有晚期 HS 的患者中。对于最佳局部治疗或最佳局部伤口护理的证据是有限的。因此，需要多学科方法来解决 HS 的所有方面，包括局部治疗、全身治疗和适当的伤口护理。本文的重点是回顾 HS 患者局部治疗和局部伤口护理策略的证据。
