患自闭症谱系障碍婴儿12个月时的语言差异
Language Differences at 12 Months in Infants Who Develop Autism Spectrum Disorder.
作者信息
Lazenby DeWayne C, Sideridis Georgios D, Huntington Noelle, Prante Matthew, Dale Philip S, Curtin Suzanne, Henkel Lisa, Iverson Jana M, Carver Leslie, Dobkins Karen, Akshoomoff Natacha, Tagavi Daina, Nelson Charles A, Tager-Flusberg Helen
机构信息
Division of Developmental Medicine, Boston Children's Hospital, Harvard Medical School, 300 Longwood Ave, Boston, MA, 02115, USA.
Joint Base Elmendorf Richardson Hospital, 1234 Juneau Ave, Jber, AK, 99505, USA.
出版信息
J Autism Dev Disord. 2016 Mar;46(3):899-909. doi: 10.1007/s10803-015-2632-1.
Little is known about early language development in infants who later develop autism spectrum disorder (ASD). We analyzed prospective data from 346 infants, some of whom were at high risk for developing ASD, to determine if language differences could be detected at 12 months of age in the infants who later were diagnosed with ASD. Analyses revealed lower receptive and expressive language scores in infants who later were diagnosed with ASD. Controlling for overall ability to understand and produce single words, a Rasch analysis indicated that infants who later developed ASD had a higher degree of statistically unexpected word understanding and production. At 12 months of age, quantitative and qualitative language patterns distinguished infants who later developed ASD from those who did not.
对于后来发展为自闭症谱系障碍（ASD）的婴儿的早期语言发展，我们所知甚少。我们分析了来自346名婴儿的前瞻性数据，其中一些婴儿有发展为ASD的高风险，以确定在12个月大时，能否在后来被诊断为ASD的婴儿中检测到语言差异。分析显示，后来被诊断为ASD的婴儿的接受性和表达性语言得分较低。在控制了理解和说出单个单词的总体能力后，一项拉施分析表明，后来发展为ASD的婴儿在单词理解和产出方面有更高程度的统计学上意外的情况。在12个月大时，定量和定性的语言模式区分了后来发展为ASD的婴儿和未发展为ASD的婴儿。
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