• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

飞扬草致急性氧化溶血并高铁血红蛋白血症:两例报告。

Acalypha indica induced acute oxidative haemolysis and methaemoglobinaemia: two case reports.

机构信息

National Hospital Kandy, Kandy, Sri Lanka.

出版信息

J Med Case Rep. 2024 Mar 19;18(1):163. doi: 10.1186/s13256-024-04481-8.

DOI:10.1186/s13256-024-04481-8
PMID:38500232
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10949590/
Abstract

BACKGROUND

Herbal products and traditional remedies are commonly used by individuals worldwide for the management of common ailments, even though most are not without risks. Acalypha indica is a popular medicinal plant consumed in some Asian countries.

CASE PRESENTATION

This case report presents a 40-year-old previously unevaluated Sri Lankan female and her 8-year-old son who presented with severe glucose-6-phosphate dehydrogenase (G6PD) deficiency related acute intravascular oxidative haemolysis and methaemoglobinaemia precipitated by Acalypha indica consumption, successfully managed with supportive care and blood transfusion.

CONCLUSIONS

This case highlights the potential hemolytic and methaemoglobinaemic effects of ingesting oxidant herbal products and the importance of considering such exposures in patients presenting with hemolysis and multiorgan involvement, particularly in communities where herbal product intake is popular. Healthcare providers should be aware of the risks associated with traditional remedies and maintain a high index of suspicion to ensure prompt recognition and appropriate management.

摘要

背景

草药产品和传统疗法在全球范围内被个人广泛用于治疗常见疾病,尽管大多数疗法并非没有风险。飞扬草是一种在一些亚洲国家被广泛使用的药用植物。

病例介绍

本病例报告介绍了一位来自斯里兰卡的 40 岁未评估的女性及其 8 岁的儿子,他们因食用飞扬草而导致严重的葡萄糖-6-磷酸脱氢酶(G6PD)缺乏相关的急性血管内氧化溶血和高铁血红蛋白血症,通过支持性治疗和输血成功治疗。

结论

本病例强调了摄入氧化剂草药产品可能导致溶血和高铁血红蛋白血症,并强调了在出现溶血和多器官受累的患者中,特别是在草药产品摄入流行的社区中,考虑这些暴露的重要性。医疗保健提供者应该了解与传统疗法相关的风险,并保持高度怀疑指数,以确保及时识别和适当管理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f02a/10949590/a4c3cf47ef6b/13256_2024_4481_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f02a/10949590/e451242136cd/13256_2024_4481_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f02a/10949590/07eb61867098/13256_2024_4481_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f02a/10949590/99c24676e938/13256_2024_4481_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f02a/10949590/a0cd81d693ed/13256_2024_4481_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f02a/10949590/a4c3cf47ef6b/13256_2024_4481_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f02a/10949590/e451242136cd/13256_2024_4481_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f02a/10949590/07eb61867098/13256_2024_4481_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f02a/10949590/99c24676e938/13256_2024_4481_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f02a/10949590/a0cd81d693ed/13256_2024_4481_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f02a/10949590/a4c3cf47ef6b/13256_2024_4481_Fig5_HTML.jpg

相似文献

1
Acalypha indica induced acute oxidative haemolysis and methaemoglobinaemia: two case reports.飞扬草致急性氧化溶血并高铁血红蛋白血症:两例报告。
J Med Case Rep. 2024 Mar 19;18(1):163. doi: 10.1186/s13256-024-04481-8.
2
induced transient glucose-6-phosphate dehydrogenase deficiency with acute haemolysis.诱导性短暂葡萄糖-6-磷酸脱氢酶缺乏伴急性溶血性贫血。
BMJ Case Rep. 2022 Mar 1;15(3):e245447. doi: 10.1136/bcr-2021-245447.
3
A vegetable-induced hemolytic crisis in a G6PD deficient person: a case report.一名葡萄糖-6-磷酸脱氢酶(G6PD)缺乏者的蔬菜诱发溶血性危机:病例报告
BMC Res Notes. 2018 Mar 14;11(1):179. doi: 10.1186/s13104-018-3286-9.
4
[Plant Traditional Treatment with Inducing Haemolysis in Patients with G6PD Deficiency: A Frequent Circumstance in Mayotte?].[植物传统疗法致葡萄糖-6-磷酸脱氢酶缺乏症患者溶血:马约特岛的常见情况?]
Bull Soc Pathol Exot. 2018;111(2):81-83. doi: 10.3166/bspe-2018-0020.
5
Acalypha indica induced haemolysis in G6PD deficiency.铁苋菜可导致葡萄糖-6-磷酸脱氢酶缺乏症患者发生溶血。
Ceylon Med J. 1994 Mar;39(1):46-7.
6
Remedy or tragedy: -induced acute oxidative hemolysis associated with acute kidney injury and infective endocarditis: An initial presentation of G6PD Deficiency: A case report.补救还是悲剧:与急性肾损伤和感染性心内膜炎相关的诱导性急性氧化溶血:葡萄糖-6-磷酸脱氢酶缺乏症的首例表现:病例报告
SAGE Open Med Case Rep. 2024 Jul 26;12:2050313X241266554. doi: 10.1177/2050313X241266554. eCollection 2024.
7
Acute intravascular haemolysis in glucose-6-phosphate dehydrogenase deficient patients following ingestion of herbal broth containing Acalypha indica.葡萄糖-6-磷酸脱氢酶缺乏患者摄入含有铁苋菜的草药汤后发生急性血管内溶血。
Trop Doct. 1996 Jan;26(1):32. doi: 10.1177/004947559602600113.
8
Acalypha indica-Induced Hemolysis and Methemoglobinemia in a Child With G6PD Deficiency.铁苋菜致一名葡萄糖-6-磷酸脱氢酶缺乏儿童溶血和高铁血红蛋白血症
Indian Pediatr. 2021 Jan 15;58(1):92-93.
9
Clinical Characteristics of Poisoning.中毒的临床特征
Int J Gen Med. 2020 Aug 25;13:539-545. doi: 10.2147/IJGM.S263199. eCollection 2020.
10
Severe acute haemolytic anaemia associated with severe methaemoglobinaemia in a G6PD-deficient man.一名葡萄糖-6-磷酸脱氢酶(G6PD)缺乏的男性出现严重急性溶血性贫血并伴有严重高铁血红蛋白血症。
BMJ Case Rep. 2018 Mar 28;2018:bcr-2017-223369. doi: 10.1136/bcr-2017-223369.

引用本文的文献

1
Glucose-6-phosphate dehydrogenase deficiency induced hemolytic anemia and methemoglobinemia: a case report in a 7 -year-old female patient.葡萄糖-6-磷酸脱氢酶缺乏症诱发的溶血性贫血和高铁血红蛋白血症:一名7岁女性患者的病例报告
Ital J Pediatr. 2025 Aug 21;51(1):258. doi: 10.1186/s13052-025-02051-2.

本文引用的文献

1
Vitamin C-induced Hemolysis: Meta-summary and Review of Literature.维生素C诱导的溶血:文献的Meta综述
Indian J Crit Care Med. 2022 Feb;26(2):224-227. doi: 10.5005/jp-journals-10071-24111.
2
induced transient glucose-6-phosphate dehydrogenase deficiency with acute haemolysis.诱导性短暂葡萄糖-6-磷酸脱氢酶缺乏伴急性溶血性贫血。
BMJ Case Rep. 2022 Mar 1;15(3):e245447. doi: 10.1136/bcr-2021-245447.
3
Acalypha indica-Induced Hemolysis and Methemoglobinemia in a Child With G6PD Deficiency.铁苋菜致一名葡萄糖-6-磷酸脱氢酶缺乏儿童溶血和高铁血红蛋白血症
Indian Pediatr. 2021 Jan 15;58(1):92-93.
4
Clinical Characteristics of Poisoning.中毒的临床特征
Int J Gen Med. 2020 Aug 25;13:539-545. doi: 10.2147/IJGM.S263199. eCollection 2020.
5
Addressing the gender-knowledge gap in glucose-6-phosphate dehydrogenase deficiency: challenges and opportunities.解决葡萄糖-6-磷酸脱氢酶缺乏症中的性别知识差距:挑战与机遇
Int Health. 2019 Jan 1;11(1):7-14. doi: 10.1093/inthealth/ihy060.
6
A vegetable-induced hemolytic crisis in a G6PD deficient person: a case report.一名葡萄糖-6-磷酸脱氢酶(G6PD)缺乏者的蔬菜诱发溶血性危机:病例报告
BMC Res Notes. 2018 Mar 14;11(1):179. doi: 10.1186/s13104-018-3286-9.
7
A review of Acalypha indica L. (Euphorbiaceae) as traditional medicinal plant and its therapeutic potential.浅析飞扬草(大戟科)作为传统药用植物及其治疗潜力。
J Ethnopharmacol. 2017 Jul 31;207:146-173. doi: 10.1016/j.jep.2017.06.019. Epub 2017 Jun 21.
8
Prevalence of G6PD deficiency in selected populations from two previously high malaria endemic areas of Sri Lanka.斯里兰卡两个先前疟疾高发流行地区特定人群中葡萄糖-6-磷酸脱氢酶(G6PD)缺乏症的患病率。
PLoS One. 2017 Feb 2;12(2):e0171208. doi: 10.1371/journal.pone.0171208. eCollection 2017.
9
Do all patients with acquired methemoglobinemia need treatment? A lesson learnt.所有获得性高铁血红蛋白血症患者都需要治疗吗?吸取的教训。
J Community Hosp Intern Med Perspect. 2015 Oct 19;5(5):29079. doi: 10.3402/jchimp.v5.29079. eCollection 2015.
10
G6PD gene variants and its association with malaria in a Sri Lankan population.葡萄糖-6-磷酸脱氢酶(G6PD)基因变异及其与斯里兰卡人群疟疾的关联。
Malar J. 2015 Feb 22;14:93. doi: 10.1186/s12936-015-0603-9.