Valdez Carrie, Sarani Babak, Young Hannah, Amdur Richard, Dunne James, Chawla Lakhmir S
Department of Medicine, The George Washington University Hospital, Washington, DC.
Department of Medicine, The George Washington University Hospital, Washington, DC.
J Surg Res. 2016 Feb;200(2):604-9. doi: 10.1016/j.jss.2015.08.031. Epub 2015 Aug 28.
BACKGROUND: The trimodal distribution of traumatic death was first described by Trunkey in 1983, which demonstrated that most deaths occur in the first 24 h. We postulate that since 1983, the time-to-death histogram described has shifted. METHODS: A retrospective analysis identifying timing of death was conducted on the National Trauma Data Bank (version 7.2) from 2002 to 2006. Early death was defined as death within 24 h of admission. International Classification of Diseases ninth edition codes with greater than 20% early deaths were called "high-risk codes". Bivariate analyses were conducted to assess the association between demographics, injury factors, and death. Pearson's χ(2) test was used to compare timing of death by region of injury. Multivariate logistic regression was conducted to show the effect of region of injury on death while controlling for demographic factors and injury type. RESULTS: The cohort includes 898,982 patients. The study population was predominantly male (66%) and Caucasian (62%). Mean age and injury severity score were 45 ± 20.3 and 11 ± 10, respectively. Overall mortality rate was 5% with 56% dying early. Head/neck, thorax, and abdomen/pelvis injuries were more prevalent in overall deaths (35%, 22%, and 11%, respectively). Thorax and abdomen/pelvis injuries predicted early death (odds ratio 2.03 and 1.39, respectively). CONCLUSIONS: The prevalence of early death has decreased since 1983, but the majority of deaths still occur within 24 h of injury. Ample opportunity remains to impact mortality in the first 24 h after injury.
背景:创伤性死亡的三峰分布最早由特伦基在1983年描述,该分布表明大多数死亡发生在最初的24小时内。我们推测,自1983年以来,所描述的死亡时间直方图已经发生了变化。 方法:对2002年至2006年国家创伤数据库(版本7.2)进行回顾性分析,以确定死亡时间。早期死亡定义为入院后24小时内死亡。早期死亡比例超过20%的国际疾病分类第九版编码被称为“高风险编码”。进行双变量分析以评估人口统计学、损伤因素与死亡之间的关联。使用Pearson卡方检验比较损伤部位的死亡时间。进行多变量逻辑回归以显示损伤部位对死亡的影响,同时控制人口统计学因素和损伤类型。 结果:该队列包括898,982名患者。研究人群以男性(66%)和白种人(62%)为主。平均年龄和损伤严重程度评分分别为45±20.3和11±10。总体死亡率为5%,其中56%为早期死亡。头部/颈部、胸部和腹部/骨盆损伤在总体死亡中更为常见(分别为35%、22%和11%)。胸部和腹部/骨盆损伤预示着早期死亡(优势比分别为2.03和1.39)。 结论:自1983年以来,早期死亡的发生率有所下降,但大多数死亡仍发生在受伤后的24小时内。在受伤后的最初24小时内,降低死亡率仍有很大机会。
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