Cajigas Hector R, Awdish Rana
Henry Ford Hospital, Detroit, MI, USA.
Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Heart Fail Rev. 2016 May;21(3):229-37. doi: 10.1007/s10741-015-9512-9.
Pulmonary hypertension has been classified into five major subgroups in order to better understand and apply knowledge from the areas of molecular biology, pathophysiology and clinical science. Accurate classification of the patient not only optimizes diagnostic approach but also confers the best benefit, as therapeutic approaches are applied accurately. Current diagnostic strategies begin with a detailed history and physical, which are directed to elucidate symptoms that may increase the degree of suspicion. Subsequent application of a logical approach to progress through the diagnostic algorithm , with understanding of the complexity of this process, allows for best possible outcomes. Proper diagnosis and classification will eventually increase the potential for appropriate research and progress toward of a possible cure for this fatal disease.
肺动脉高压已被分为五个主要亚组，以便更好地理解和应用分子生物学、病理生理学和临床科学领域的知识。对患者进行准确分类不仅能优化诊断方法，还能带来最大益处，因为治疗方法能得到准确应用。当前的诊断策略始于详细的病史和体格检查，旨在阐明可能增加怀疑程度的症状。随后采用逻辑方法逐步推进诊断流程，同时理解这一过程的复杂性，这样才能取得最佳结果。正确的诊断和分类最终将增加进行适当研究的可能性，并推动朝着治愈这种致命疾病取得进展。
