Provencher S, Martel S, Jais X, Sitbon O, Humbert M, Simonneau G
Institut de cardiologie et de pneumologie de l'université Laval, service de pneumologie, Hôpital Laval, Québec, Canada.
Presse Med. 2005 Nov 5;34(19 Pt 2):1435-44. doi: 10.1016/s0755-4982(05)84205-8.
The clinical classification of types of pulmonary hypertension has made it possible to better standardize the approach to the diagnosis and treatment of patients, to perform clinical studies among homogeneous patients, and to discover common laboratory abnormalities that may serve as markers or help elucidate mechanisms of disease. Pulmonary arterial hypertension groups together different diseases that affect the small-caliber pulmonary arteries and lead to a progressive increase in pulmonary arterial resistance and right heart failure. A specific diagnosis of pulmonary arterial hypertension is generally based on a detailed and methodical clinical evaluation. Pulmonary biopsy is rarely indicated. Work-up in a center specialized in the management of this disease is frequently appropriate when the cause of the hypertension is not clear or when a specific treatment is envisaged.
肺动脉高压类型的临床分类使得更好地规范患者的诊断和治疗方法、在同质患者中开展临床研究以及发现可能作为标志物或有助于阐明疾病机制的常见实验室异常成为可能。动脉性肺动脉高压将影响小口径肺动脉并导致肺动脉阻力逐渐增加和右心衰竭的不同疾病归为一类。动脉性肺动脉高压的明确诊断通常基于详细且系统的临床评估。肺活检很少有必要。当高血压病因不明或考虑进行特定治疗时，在专门管理这种疾病的中心进行检查通常是合适的。
