Kobus Thiele, McDannold Nathan
Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, 221 Longwood Avenue, #521, Boston, MA 02115, USA; Department of Radiology and Nuclear Medicine, Radboud University Medical Center, Geert Grooteplein 10, 6500 HB, Nijmegen, Netherlands.
Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, 221 Longwood Avenue, #521, Boston, MA 02115, USA.
Magn Reson Imaging Clin N Am. 2015 Nov;23(4):657-67. doi: 10.1016/j.mric.2015.05.013. Epub 2015 Jul 7.
In this review, several clinical applications of magnetic resonance (MR)-guided focused ultrasound (FUS) are updated. MR-guided FUS is used clinically for thermal ablation of uterine fibroids and bone metastases. Thousands of patients have successfully been treated. Transcranial MR-guided FUS has received CE certification for ablation of deep, central locations in the brain. Thermal ablation of specific parts of the thalamus can result in relief of the symptoms in a number of neurological disorders. Several approaches have been proposed for ablation of prostate and breast cancer and clinical trials should show the potential of MR-guided FUS for these and other applications.
在本综述中，磁共振（MR）引导聚焦超声（FUS）的几种临床应用得到了更新。MR引导FUS在临床上用于子宫肌瘤和骨转移瘤的热消融。数千名患者已成功接受治疗。经颅MR引导FUS已获得CE认证，用于脑部深部、中央部位的消融。丘脑特定部位的热消融可缓解多种神经系统疾病的症状。针对前列腺癌和乳腺癌的消融已提出了几种方法，临床试验应能显示MR引导FUS在这些及其他应用中的潜力。
