Trumm C G, Napoli A, Peller M, Clevert D-A, Stahl R, Reiser M, Matzko M
Institut für Klinische Radiologie, Klinikum der Ludwig-Maximilians-Universität München-Großhadern, Marchioninistrasse 15, Munich, Germany.
Radiologe. 2013 Mar;53(3):200-8. doi: 10.1007/s00117-012-2417-x.
High-intensity focused ultrasound (synonyms FUS and HIFU) under magnetic resonance imaging (MRI) guidance (synonyms MRgFUS and MR-HIFU) is a completely non-invasive technology for accurate thermal ablation of a target tissue while neighboring tissues and organs are preserved.
The combination of FUS with MRI for planning, (near) real-time monitoring and outcome assessment of treatment markedly enhances the safety of the procedure.
The MRgFUS procedure is clinically established in particular for the treatment of symptomatic uterine fibroids, followed by palliative ablation of painful bone metastases. Furthermore, promising results have been shown for the treatment of adenomyosis, malignant tumors of the prostate, breast and liver and for various intracranial applications, such as thermal ablation of brain tumors, functional neurosurgery and transient disruption of the blood-brain barrier.
在磁共振成像（MRI）引导下的高强度聚焦超声（同义词：FUS和HIFU）（同义词：MRgFUS和MR - HIFU）是一种完全非侵入性技术，可在保留邻近组织和器官的同时对目标组织进行精确热消融。
FUS与MRI相结合用于治疗规划、（近）实时监测和疗效评估，显著提高了该手术的安全性。
MRgFUS手术在临床上尤其用于治疗有症状的子宫肌瘤，其次是对疼痛性骨转移瘤进行姑息性消融。此外，在子宫腺肌病、前列腺、乳腺和肝脏恶性肿瘤的治疗以及各种颅内应用方面，如脑肿瘤热消融、功能神经外科手术和血脑屏障的短暂破坏，均已显示出有前景的结果。
