Baharvand Maryam, Jafari Soudeh, Mortazavi Hamed
Professor, Department of Oral Medicine, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Assistant Professor, Department of Oral Medicine, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
J Clin Diagn Res. 2017 Mar;11(3):ZE05-ZE11. doi: 10.7860/JCDR/2017/21703.9467. Epub 2017 Mar 1.
Oral mucositis is an inflammatory mucosal destruction as a result of chemotherapy and/or radiation therapy, which in severe cases can impair patients' quality of life. Moreover, mucosal infection and/or systemic involvement due to compromised immunity leads to delay or discontinuation of the treatment. Many strategies and agents have been suggested for the management of this condition. Because of their lower side effects compared to chemical drugs, general interest in evaluating therapeutic effects of herbs has been increased intensively. Herbal plants apply their effect through different mechanisms of action: antioxidant, analgesic, anti-inflammatory, antifungal, antiseptic, and anticarcinogenic activity. Recently, various natural agents in plants have been noticed in mucositis, which may improve the symptoms through different interventions. The purpose of this review is to focus on the preventive or therapeutic use of herbal medicine to alleviate oral mucositis.
口腔黏膜炎是化疗和/或放疗导致的一种炎症性黏膜破坏，严重时会损害患者的生活质量。此外，免疫功能受损引起的黏膜感染和/或全身受累会导致治疗延迟或中断。针对这种情况，人们提出了许多治疗策略和药物。由于草药与化学药物相比副作用较小，因此对评估草药治疗效果的普遍兴趣大幅增加。草药植物通过不同的作用机制发挥作用：抗氧化、止痛、抗炎、抗真菌、防腐和抗癌活性。最近，植物中的各种天然成分在黏膜炎方面受到关注，它们可能通过不同的干预措施改善症状。本综述的目的是聚焦于草药在预防或治疗口腔黏膜炎方面的应用。
