Bingley P J, Gale E A
Department of Diabetes and Immunogenetics, St. Bartholomew's Hospital, London, England, United Kingdom.
Diabetes Care. 1989 Apr;12(4):289-95. doi: 10.2337/diacare.12.4.289.
A rising incidence of insulin-dependent diabetes mellitus (IDDM) has been reported in many northern European countries, with a rate equivalent to a doubling time of 20-30 yr in some. North American and Japanese studies report a similar trend, although they are less uniform in their findings. Although the number of genetically susceptible individuals within these populations has increased, the rapidity of the change suggests that environmental factors are responsible. If these could be identified, primary prevention might become possible.
许多北欧国家报告称胰岛素依赖型糖尿病(IDDM)的发病率呈上升趋势,在一些国家发病率的倍增时间相当于20至30年。北美和日本的研究也报告了类似趋势,尽管他们的研究结果不太一致。虽然这些人群中遗传易感性个体的数量有所增加,但这种变化的迅速性表明环境因素起了作用。如果能够识别出这些因素,一级预防或许就有可能实现。