Teping C, Reim M
Augenklinik der Medizinischen Fakultät der RWTH Aachen.
Klin Monbl Augenheilkd. 1989 Jan;194(1):1-5. doi: 10.1055/s-2008-1046325.
A special danger in cases of severe chemical and thermal eye burns is the development of corneoscleral ulceration. To treat these most severe burns tenonplasty was developed as a new surgical treatment. The principle of tenonplasty is based on a plastic operation in which vital connective tissue of the orbit is used. First, all necrotic tissue is removed from the conjunctiva and sclera. The Tenon tissue is then bluntly separated from the equatorial region of the globe and from extraocular muscles. It is important to keep its blood vessels intact and to prepare the Tenon sheet with a smooth surface, because regenerating conjunctival epithelium has to slide on this layer. After preparation, the elastic Tenon flap can be moved to the limbus and sutured tightly to the sclera, thus providing a revascularization of the denuded sclera and the limbus region. In all patients the scleral ulceration healed and the eyes were saved from anterior segment necrosis. Although rapid regeneration of conjunctival epithelium on the Tenon layer always occurred rapidly, the cornea was completely covered by new epithelium in only a few cases: an artificial epithelium was therefore applied early in most patients. After tenonplasty and application of an artificial epithelium high local doses of corticosteroids can be given to suppress reactive inflammation and prevent neovascularization of the cornea.
在严重化学性和热性眼烧伤病例中,一个特殊的危险是角膜巩膜溃疡的形成。为了治疗这些最严重的烧伤,开发了一种新的手术治疗方法——眼球筋膜成形术。眼球筋膜成形术的原理基于一种整形手术,即使用眼眶的重要结缔组织。首先,从结膜和巩膜上清除所有坏死组织。然后将眼球筋膜组织从眼球赤道区域和眼外肌钝性分离。保持其血管完整并制备表面光滑的眼球筋膜片很重要,因为再生的结膜上皮必须在这一层上滑动。制备完成后,可将弹性眼球筋膜瓣移至角膜缘并紧密缝合至巩膜,从而为裸露的巩膜和角膜缘区域提供血管再生。所有患者的巩膜溃疡均愈合,眼睛避免了前段坏死。尽管眼球筋膜层上的结膜上皮总是迅速再生,但只有少数病例角膜被新上皮完全覆盖:因此,大多数患者早期都应用了人工上皮。在眼球筋膜成形术和应用人工上皮后,可给予高局部剂量的皮质类固醇以抑制反应性炎症并防止角膜新生血管形成。