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[严重化学性眼烧伤的眼球筋膜囊成形术及早期角膜移植术]

[Tenon-plasty and early keratoplasty in severe chemical eye burns].

作者信息

Kuckelkorn R, Redbrake C, Kottek A, Feldmann P, Reim M

机构信息

Augenklinik der RWTH Aachen.

出版信息

Ophthalmologe. 1995 Aug;92(4):439-44.

PMID:7549326
Abstract

In severe eye burns with destruction of extensive areas of the conjunctiva and epibulbar tissue, Tenon plasty has proved to be successful. Because the epithelium fails to cover the denuded stroma, the corneal surface must be protected by an artificial epithelium. If necrolysis occurs, a tectonic keratoplasty must be performed early. The clinical courses of 12 patients with 14 very severely burned eyes are reported. In addition to Tenon plasty, early penetrating keratoplasies with large diameters 10-16 mm were performed up to 3 months after the accident. The follow-up time was between 6 and 34 months (mean 15.1 months). In five cases the Tenon tissue showed marked inflammation, and the keratoplasties developed large, persistent epithelial defects and had to be covered by conjunctiva. In the other cases it was possible to preserve a healthy epithelial layer by applying soft contact lenses. In 79% of the cases an endothelial graft rejection was observed. In about 50% the transplants were lost. Early keratoplasties are mainly for tectonic repair in severely burned eyes. Optical rehabilitation was achieved in only a few cases.

摘要

在伴有大面积结膜和眼球表面组织破坏的严重眼部烧伤中,眼球筋膜成形术已被证明是成功的。由于上皮细胞无法覆盖裸露的基质,角膜表面必须由人工上皮来保护。如果发生坏死溶解,则必须尽早进行结构性角膜移植术。本文报告了12例患者14只严重烧伤眼的临床病程。除眼球筋膜成形术外,在事故发生后3个月内还进行了直径为10 - 16毫米的早期穿透性角膜移植术。随访时间为6至34个月(平均15.1个月)。5例患者的眼球筋膜组织出现明显炎症,角膜移植术后出现大面积、持续性上皮缺损,不得不采用结膜覆盖。在其他病例中,通过佩戴软性隐形眼镜得以保留健康的上皮层。79%的病例观察到内皮移植排斥反应。约50%的移植眼失败。早期角膜移植术主要用于严重烧伤眼的结构性修复。仅少数病例实现了视力康复。

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