Suppr超能文献

[德国DVPZ前列腺中心的前列腺癌治疗图谱]

[Treatment mapping of prostate cancer in DVPZ prostate centers in Germany].

作者信息

Berges R, Ebert T, Schafhauser W, Schultze-Seemann W, Braun M, Herden J, Weib P, Garcia Schürmann M, Reimann M, Bornhof C, Oberpenning F, Baur P, Zumbé J, Gronau E, Diederichs W, Brinkman O A, Goepel M, Göll A, Hoefner K, Kriegmair M, Laabs S, Planz B, Platz G, Heidenreich A

机构信息

PZ Köln (Campus Longerich, Campus Universitätsklinikum), Köln, Deutschland.

Dachverband der Prostatazentren Deutschlands e.V., Claire-Waldoff-Straße 3, 10117, Berlin, Deutschland.

出版信息

Urologe A. 2015 Nov;54(11):1546, 1548-54. doi: 10.1007/s00120-015-3843-y.

Abstract

BACKGROUND

In prostate centers of the Governing Body of German Prostate Centers (DVPZ, Dachverband der Prostatazentren Deutschlands e.V.) treatment data from 3 university clinics, 21 treatment clinics, 3 private clinics and 330 general practitioners incorporated under 22 certificates are collated, in order to document the quality and type of cross-sectoral and interdisciplinary treatment, in particular of prostate cancer (PCA) patients.

METHODS

This analysis is based on the DVPZ UroCloud data sets from 20 July 2015. The UroCloud reflects the web-based chronological disease development and quality parameters. For the descriptive analysis of particular key figures, available complete data sets were selected.

RESULTS

Of the centers 22 held a valid certificate and fulfilled all required case numbers and structural prerequisites at the primary certification or recertification. In three cases a reauditing led to requirements before certification. Since 2005 a total of 9650 PCA patients have been pseudonymized and followed up (41,247 follow-up forms, 4.3 forms per patient). In 2014 the median number of newly documented PCA patients was 61 per center (minimum 7 and maximum 295). Radical prostatectomy (RP) dominated with 4491 (56 %) cases followed by primary hormonal therapy (1210 cases, 15 %), irradiation (809, 10 %) and non-interventional therapy, such as active surveillance (AS) or watchful waiting (WW) in 760 cases (10 %). A prostate-specific antigen (PSA) reduction was documented in 50 % of the patients with a preoperative PSA value > 20, in 60 % of pT4 tumors and in 50 % of patients with a tumor Gleason score of 9-10. A positive incision margin (R+) was found in in 15 % of pT2 stages, 41 % of pT3 stages and 85 % of pT4 stages. A secondary intervention was documented in 6.5 % of RP.

CONCLUSION

The DVPZ certificate reflects the complete spectrum of treatment of PCA patients. The strength of the certificate lies in the documentation of patient development and a simultaneous collation of quality parameters.

摘要

背景

在德国前列腺中心管理机构(DVPZ,德国前列腺中心联合会)的前列腺中心,整理了来自3家大学诊所、21家治疗诊所、3家私立诊所及330名全科医生(纳入22份证书)的治疗数据,以记录跨部门和跨学科治疗的质量和类型,尤其是前列腺癌(PCA)患者的治疗情况。

方法

本分析基于2015年7月20日的DVPZ UroCloud数据集。UroCloud反映了基于网络的按时间顺序排列的疾病发展和质量参数。对于特定关键数据的描述性分析,选择了可用的完整数据集。

结果

22个中心持有有效证书,并在初次认证或重新认证时满足所有所需病例数和结构前提条件。有3个案例在认证前需重新审核。自2005年以来,共有9650例PCA患者进行了匿名化处理并接受随访(41247份随访表格,每位患者4.3份表格)。2014年,每个中心新记录的PCA患者中位数为61例(最少7例,最多295例)。根治性前列腺切除术(RP)占主导,有4491例(56%),其次是一线激素治疗(1210例,15%)、放疗(809例,10%)以及非介入性治疗,如主动监测(AS)或观察等待(WW),共760例(10%)。术前前列腺特异性抗原(PSA)值>20的患者中,50%记录到PSA降低;pT4肿瘤患者中,60%记录到PSA降低;肿瘤Gleason评分为9 - 10的患者中,50%记录到PSA降低。pT2期患者中,15%切缘阳性(R+);pT3期患者中,41%切缘阳性;pT4期患者中,85%切缘阳性。RP患者中有6.5%记录到二次干预。

结论

DVPZ证书反映了PCA患者的完整治疗范围。该证书的优势在于记录患者病情发展并同时整理质量参数。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验