Hao Wei, Wang Han, Ye Qingyu, Zhang Wen-Xiong, Xi Zhenfeng
Beijing National Laboratory for Molecular Sciences (BNLMS) and Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry, Peking University , Beijing 100871, China.
Org Lett. 2015 Nov 20;17(22):5674-7. doi: 10.1021/acs.orglett.5b02959. Epub 2015 Nov 2.
The cyclopentadiene-phosphine ligand (L1) and palladium were found to be an efficient catalyst system to activate the α-C(sp(2))-H bond of pyrrole and indole derivatives. Various alkenyl or aryl dibromides could be used to react with pyrrole and indole derivatives to afford multisubstituted indolizines in high yields.
环戊二烯膦配体（L1）和钯被发现是一种有效的催化体系，可活化吡咯和吲哚衍生物的α-C(sp(2))-H键。各种烯基或芳基二溴化物可用于与吡咯和吲哚衍生物反应，以高产率得到多取代中氮茚。
