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[宿主抗噬菌体机制的研究进展]

[Advances of Researches on Anti-phage Mechanisms of Host].

作者信息

Mao Pujia, Zeng Weikun, Hong Yu, Feng Mengdie, Xu Zeyang

出版信息

Bing Du Xue Bao. 2015 Jul;31(4):474-9.

Abstract

Phages also known as bacteria viruses, are recognized as the most abundant and diverse microbes. This diversity is adapting to the selective pressures such as the prevalence of the phage resistance mechanisms of bacteria. Phages invade and lyse bacterial through six steps (adsorption, injection, replication, transcription translation, assemble, release). Bacteria evolve to many anti-phage mechanisms to avoid phage infection and lysis. This paper focus on a variety of anti-phage mechanisms of bacteria.

摘要

噬菌体也被称为细菌病毒,是已知数量最多、种类最丰富的微生物。这种多样性是为了适应诸如细菌噬菌体抗性机制普遍存在等选择压力。噬菌体通过六个步骤(吸附、注入、复制、转录翻译、组装、释放)侵入并裂解细菌。细菌进化出多种抗噬菌体机制以避免噬菌体感染和裂解。本文重点关注细菌的多种抗噬菌体机制。

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