Ren Wen, Damayanti Nur P, Wang Xiaolei, Irudayaraj Joseph M K
Agricultural and Biological Engineering, Bindley Bioscience Center, Purdue Center for Cancer Research, Purdue University, West Lafayette, IN 47907, USA.
Chem Commun (Camb). 2016 Jan 7;52(2):410-3. doi: 10.1039/c5cc06566f. Epub 2015 Nov 3.
We propose an ultrasensitive SERS-based peptide biosensor platform to monitor phosphorylation catalyzed by kinase in a dynamic format. The developed SERS strategy has a short response time with potential to monitor phosphorylation in live cells.
我们提出了一种基于表面增强拉曼散射(SERS)的超灵敏肽生物传感器平台,以动态方式监测激酶催化的磷酸化反应。所开发的SERS策略响应时间短,具有监测活细胞中磷酸化反应的潜力。