Abrahão M I, Gomiero A B, Peccin M S, Grande A J, Trevisani V F M
a Federal University of São Paulo , São Paulo.
b Federal University of São Paulo , Santos.
Scand J Rheumatol. 2016;45(3):197-201. doi: 10.3109/03009742.2015.1094126. Epub 2015 Nov 3.
To compare the efficacy of cardiovascular training (CT) with resistance training (RT) in improving the health-related quality of life (HRQoL) and physical function of patients with systemic lupus erythematosus (SLE).
A randomized controlled trial was conducted with participants randomly allocated to either a CT (n = 21), RT (n = 21), or control group (n = 21). The outcomes assessed were: HRQoL using the Medical Outcomes Study 36-Item Short Form Health Survey (SF-36), severity of depression using the Beck Depression Inventory (BDI), disease activity using the SLE Disease Activity Index (SLEDAI), and aerobic capacity using a 12-minute walk test (T12).
Sixty-three patients (61 women and two men), aged 42.9 ± 14.4 years, with a mean body mass index (BMI) of 28.7 ± 10.6 kg/m(2), disease duration of 3.8 ± 3.3 years, and not physically active participated in the study. HRQoL improved for both exercise groups but was superior in the RT group. There was no significant difference in physical function between the intervention groups, except for aerobic capacity. Neither training programme was associated with a change in disease activity.
Exercise intervention proved to be better than not exercising. CT was better than RT in improving HRQoL.
比较心血管训练（CT）与阻力训练（RT）对改善系统性红斑狼疮（SLE）患者健康相关生活质量（HRQoL）和身体功能的效果。
进行一项随机对照试验，参与者被随机分配到CT组（n = 21）、RT组（n = 21）或对照组（n = 21）。评估的结果包括：使用医学结局研究36项简短健康调查（SF - 36）评估HRQoL，使用贝克抑郁量表（BDI）评估抑郁严重程度，使用SLE疾病活动指数（SLEDAI）评估疾病活动度，以及使用12分钟步行试验（T12）评估有氧运动能力。
63例患者（61名女性和2名男性）参与了研究，年龄42.9±14.4岁，平均体重指数（BMI）为28.7±10.6kg/m²，病程3.8±3.3年，且均无规律运动。两个运动组的HRQoL均有所改善，但RT组更优。除有氧运动能力外，干预组之间的身体功能无显著差异。两种训练方案均与疾病活动度的变化无关。
运动干预证明优于不运动。在改善HRQoL方面，CT优于RT。
