运动对风湿性疾病患者抑郁的影响：一项系统评价和荟萃分析。
Effects of exercise on depression in patients with rheumatic diseases: a systematic review and meta-analysis.
作者信息
Bao Yanfeng, Liang Qian, Ji Juan, Cheng Chun, Dong Chen, Zhao Rui
机构信息
Nanjing University of Traditional Chinese Medicine, 210023, Nanjing, China.
Department of Rheumatology, Affiliated Hospital of Nantong University, 226001, Nantong, China.
出版信息
Z Rheumatol. 2024 Feb;83(Suppl 1):40-47. doi: 10.1007/s00393-023-01321-w. Epub 2023 Apr 20.
OBJECTIVE
To assess the effects of exercise intervention on depression in rheumatic diseases by means of a meta-analysis.
METHODS
The Cochrane Library, Embase, Medline, PubMed, and relevant records were searched. The qualities of randomized controlled trials were evaluated. Meta-analysis of the obtained related data was completed using RevMan 5.3. Heterogeneity was also evaluated with χ test and I.
RESULTS
Twelve RCTs were reviewed. Compared with baseline, the meta-analysis results showed that there was significant difference in the improvement of depression assessed by HADs, BDI, CES‑D, and AIMS in patients with rheumatic diseases (post exercise vs. baseline, -0.73 [-1.05, -0.4], P < 0.0001, I = 0%). In subgroup analysis, although none of these trends in BDI and CES‑D subgroups were significant at P < 0.05, there were clear trends towards improvement in depression.
CONCLUSION
As an alternative or supplementary treatment, the effect of exercise on rheumatism is obvious. Rheumatologists can consider exercise as an integral part of the treatment of patients with rheumatism.
目的
通过荟萃分析评估运动干预对风湿性疾病患者抑郁的影响。
方法
检索Cochrane图书馆、Embase、Medline、PubMed及相关记录。对随机对照试验的质量进行评估。使用RevMan 5.3对获得的相关数据进行荟萃分析。还采用χ检验和I²评估异质性。
结果
回顾了12项随机对照试验。荟萃分析结果显示，与基线相比，风湿性疾病患者通过医院焦虑抑郁量表（HADS）、贝克抑郁量表（BDI）、流调中心用抑郁量表（CES-D）和简明精神病评定量表（AIMS）评估的抑郁改善情况存在显著差异（运动后与基线相比，-0.73 [-1.05, -0.4]，P＜0.0001，I²=0%）。在亚组分析中，尽管BDI和CES-D亚组中的这些趋势均未在P＜0.05水平上具有显著性，但抑郁改善趋势明显。
结论
作为一种替代或辅助治疗方法，运动对风湿病的疗效显著。风湿病学家可将运动视为风湿病患者治疗的一个组成部分。
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