以密码子的速度进行合成。
Synthesis at the Speed of Codons.
机构信息
Department of Molecular Biology and Genetics, Johns Hopkins School of Medicine, Baltimore, MD, USA.
Department of Molecular Biology and Genetics, Johns Hopkins School of Medicine, Baltimore, MD, USA.
出版信息
Trends Biochem Sci. 2015 Dec;40(12):717-718. doi: 10.1016/j.tibs.2015.10.005. Epub 2015 Oct 31.
The possibility that different mRNA sequences encoding identical peptides are translated dissimilarly has long been of great interest. Recent work by Yu and co-workers provides striking evidence that mRNA sequences influence the rate of protein synthesis, and lends support to the emerging idea that mRNA sequence informs protein folding.
不同的 mRNA 序列编码相同的肽被翻译出不同的结果这一可能性一直以来都备受关注。最近由 Yu 及其同事开展的一项研究工作提供了引人注目的证据，表明 mRNA 序列会影响蛋白质合成的速度，并支持了一个新兴观点，即 mRNA 序列会影响蛋白质折叠。
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