Brandt Mary E, Lockhart Shawn R
Mycotic Diseases Branch, Centers for Disease Control and Prevention, 1600 Clifton Road; Mailstop G-11, Atlanta, GA 30333, USA.
Curr Fungal Infect Rep. 2012 Sep;6(3):170-177. doi: 10.1007/s12281-012-0094-x.
Increases in susceptible patient populations and advances in identification methods have resulted in the continued recognition of novel yeasts as agents of human infection. Most of these agents are members of the well-recognized genera , , , and . Some of these agents are "cryptic species," members of species complexes, and may not be detectable using classical carbohydrate assimilation-based methods of yeast identification. Such species require DNA- or MALDI-based methods for correct identification, although sporadic isolates may not routinely require delineation to the individual species level. The coming end of the fungal taxonomy rules requiring separate names for sexual and asexual forms of the same fungus will hopefully allow greater clarity, as names for medically important yeast can now be based on the needs of the medical mycology community and the common goal of better communication between laboratory and clinician.
易感患者群体的增加以及鉴定方法的进步,使得新型酵母菌不断被确认为人类感染的病原体。这些病原体大多是公认的属、、、和的成员。其中一些病原体是“隐性物种”,属于物种复合体的成员,使用基于经典碳水化合物同化的酵母菌鉴定方法可能无法检测到。这类物种需要基于DNA或基质辅助激光解吸电离(MALDI)的方法来进行正确鉴定,尽管偶尔分离出的菌株可能通常不需要划分到单个物种水平。要求为同一真菌的有性和无性形式使用不同名称的真菌分类规则即将结束,这有望带来更大的清晰度,因为现在医学上重要酵母菌的名称可以基于医学真菌学界的需求以及实验室与临床医生之间更好沟通的共同目标来确定。