Amrabadi Omidreza, Oryan Ahmad, Moazeni Mohammad, Sharifiyazdi Hassan, Akbari Maryam
Department of Pathology, School of Veterinary Medicine, Shiraz University, Shiraz, Iran.
Department of Pathology, School of Veterinary Medicine, Shiraz University, Shiraz, Iran.
Vet Parasitol. 2015 Dec 15;214(3-4):333-6. doi: 10.1016/j.vetpar.2015.10.021. Epub 2015 Oct 24.
Coenurosis is a debilitating disease caused by the larval stage of Taenia multiceps. The larval stage of T. multiceps appears in two cerebral and non-cerebral forms known as Coenurus cerebralis and Coenurus gaigeri,respectively. This leads to the hypothesis that there are genetic intraspecific variabilities within this species. Molecular analysis in the present study showed that C. cerebralis and C. gaigeri were 100% genetically identical based on exonic region of enolase (ENO) gene and both mitochondrial (cox1 and nad1) markers. In addition, an intronic mutation at ENO gene (position: 1171) was detected in the Iranian C. cerebralis. The phylogenetic analyses based on the ENO, cox1, nad1 sequence data also suggest that T. gaigeri may not be distinct from T. multiceps and there is only one single valid species within T. multiceps.
多头蚴病是由多头绦虫的幼虫阶段引起的一种使人衰弱的疾病。多头绦虫的幼虫阶段分别以两种脑型和非脑型出现，即脑多头蚴和盖氏多头蚴。这就引出了一个假设，即该物种内存在遗传种内变异性。本研究中的分子分析表明，基于烯醇化酶（ENO）基因的外显子区域以及两个线粒体（cox1和nad1）标记，脑多头蚴和盖氏多头蚴在基因上100%相同。此外，在伊朗的脑多头蚴中检测到ENO基因的一个内含子突变（位置：1171）。基于ENO、cox1、nad1序列数据的系统发育分析也表明，盖氏多头绦虫可能与多头绦虫没有区别，并且多头绦虫中只有一个有效物种。
