• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

非医务人员在太空探索任务中进行快速顺序诱导后插管:在火星模拟环境中的一项模拟先导研究。

Intubation after rapid sequence induction performed by non-medical personnel during space exploration missions: a simulation pilot study in a Mars analogue environment.

作者信息

Komorowski Matthieu, Fleming Sarah

机构信息

Department of Bioengineering, Imperial College London, London, SW7 2AZ UK.

University of Leicester, Maurice Shock Building, University Rd, Leicester, LE1 9HN UK.

出版信息

Extrem Physiol Med. 2015 Nov 1;4:19. doi: 10.1186/s13728-015-0038-5. eCollection 2015.

DOI:10.1186/s13728-015-0038-5
PMID:26527252
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4628782/
Abstract

BACKGROUND

The question of the safety of anaesthetic procedures performed by non anaesthetists or even by non physicians has long been debated. We explore here this question in the hypothetical context of an exploration mission to Mars. During future interplanetary space missions, the risk of medical conditions requiring surgery and anaesthetic techniques will be significant. On Earth, anaesthesia is generally performed by well accustomed personnel. During exploration missions, onboard medical expertise might be lacking, or the crew doctor could become ill or injured. Telemedical assistance will not be available. In these conditions and as a last resort, personnel with limited medical training may have to perform lifesaving procedures, which could include anaesthesia and surgery. The objective of this pilot study was to test the ability for unassisted personnel with no medical training to perform oro-tracheal intubation after a rapid sequence induction on a simulated deconditioned astronaut in a Mars analogue environment. The experiment made use of a hybrid simulation model, in which the injured astronaut was represented by a torso manikin, whose vital signs and hemodynamic status were emulated using a patient simulator software. Only assisted by an interactive computer tool (PowerPoint(®) presentation), five participants with no previous medical training completed a simplified induction of general anaesthesia with intubation.

RESULTS

No major complication occurred during the simulated trials, namely no cardiac arrest, no hypoxia, no cardiovascular collapse and no failure to intubate. The study design was able to reproduce many of the constraints of a space exploration mission.

CONCLUSIONS

Unassisted personnel with minimal medical training and familiarization with the equipment may be able to perform advanced medical care in a safe and efficient manner. Further studies integrating this protocol into a complete anaesthetic and surgical scenario will provide valuable input in designing health support systems for space exploration missions.

摘要

背景

由非麻醉医生甚至非医生进行麻醉操作的安全性问题长期以来一直存在争议。我们在此探讨在火星探索任务这一假设背景下的该问题。在未来的星际太空任务中,出现需要手术和麻醉技术的医疗状况的风险将很大。在地球上,麻醉通常由经验丰富的人员进行。在探索任务中,可能缺乏机载医疗专业知识,或者随队医生可能生病或受伤。远程医疗援助也无法提供。在这些情况下,作为最后的手段,接受过有限医学培训的人员可能不得不实施救生程序,这可能包括麻醉和手术。这项试点研究的目的是测试在火星模拟环境中,未经医学培训的无辅助人员在快速顺序诱导后对模拟失健宇航员进行口气管插管的能力。该实验使用了一种混合模拟模型,其中受伤的宇航员由一个躯干人体模型代表,其生命体征和血流动力学状态通过患者模拟器软件进行模拟。仅在一个交互式计算机工具(PowerPoint(®)演示文稿)的辅助下,五名没有医学培训经历的参与者完成了简化的全身麻醉诱导及插管操作。

结果

在模拟试验期间未发生重大并发症,即未出现心脏骤停、低氧血症、心血管虚脱和插管失败。该研究设计能够重现太空探索任务的许多限制因素。

结论

接受过极少医学培训且熟悉设备的无辅助人员可能能够安全、高效地实施高级医疗护理。将该方案整合到完整的麻醉和手术场景中的进一步研究,将为太空探索任务的健康支持系统设计提供有价值的参考。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/773b/4628782/ba59cf5cfcc8/13728_2015_38_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/773b/4628782/cc1fa735a4f0/13728_2015_38_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/773b/4628782/61315af375e4/13728_2015_38_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/773b/4628782/84855254684d/13728_2015_38_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/773b/4628782/b9e6807df51a/13728_2015_38_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/773b/4628782/ba59cf5cfcc8/13728_2015_38_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/773b/4628782/cc1fa735a4f0/13728_2015_38_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/773b/4628782/61315af375e4/13728_2015_38_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/773b/4628782/84855254684d/13728_2015_38_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/773b/4628782/b9e6807df51a/13728_2015_38_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/773b/4628782/ba59cf5cfcc8/13728_2015_38_Fig5_HTML.jpg

相似文献

1
Intubation after rapid sequence induction performed by non-medical personnel during space exploration missions: a simulation pilot study in a Mars analogue environment.非医务人员在太空探索任务中进行快速顺序诱导后插管:在火星模拟环境中的一项模拟先导研究。
Extrem Physiol Med. 2015 Nov 1;4:19. doi: 10.1186/s13728-015-0038-5. eCollection 2015.
2
Anaesthesia in austere environments: literature review and considerations for future space exploration missions.严峻环境下的麻醉:文献综述及对未来太空探索任务的思考
NPJ Microgravity. 2018 Feb 23;4:5. doi: 10.1038/s41526-018-0039-y. eCollection 2018.
3
3D Printed Surgical Instruments Evaluated by a Simulated Crew of a Mars Mission.由模拟火星任务机组人员评估的3D打印手术器械
Aerosp Med Hum Perform. 2016 Sep;87(9):806-10. doi: 10.3357/AMHP.4281.2016.
4
Medical Event Management for Future Deep Space Exploration Missions to Mars.未来火星深空探索任务的医疗事件管理。
J Surg Res. 2020 Feb;246:305-314. doi: 10.1016/j.jss.2019.09.065. Epub 2019 Nov 12.
5
Human Factor Studies on a Mars Analogue During Crew 100b International Lunar Exploration Working Group EuroMoonMars Crew: Proposed New Approaches for Future Human Space and Interplanetary Missions.在国际月球探索工作组第100b号欧洲月球火星乘员组的一次火星模拟任务期间的人为因素研究:为未来人类太空和星际任务提出的新方法。
N Am J Med Sci. 2012 Nov;4(11):548-57. doi: 10.4103/1947-2714.103313.
6
Autonomous medical care for exploration class space missions.探索类太空任务的自主医疗护理
J Trauma. 2008 Apr;64(4 Suppl):S354-63. doi: 10.1097/TA.0b013e31816c005d.
7
Anaesthesia in outer space: the ultimate ambulatory setting?外层空间的麻醉:终极门诊环境?
Curr Opin Anaesthesiol. 2016 Dec;29(6):649-654. doi: 10.1097/ACO.0000000000000390.
8
Virtual reality based surgical assistance and training system for long duration space missions.
Stud Health Technol Inform. 2001;81:315-21.
9
Lessons from a Space Analog on Adaptation for Long-Duration Exploration Missions.长期探索任务适应性太空模拟实验的经验教训。
Aerosp Med Hum Perform. 2016 Apr;87(4):406-10. doi: 10.3357/AMHP.4489.2016.
10
Adequacy of in-mission training to treat tibial shaft fractures in mars analogue testing.模拟火星任务中治疗胫骨骨干骨折的在轨训练充足性。
Sci Rep. 2023 Oct 23;13(1):18072. doi: 10.1038/s41598-023-43878-1.

引用本文的文献

1
Evaluation of free-floating tracheal intubation in weightlessness via ice-pick position with a direct laryngoscopy and classic approach with indirect videolaryngoscopy.通过直接喉镜的冰锥位和间接视频喉镜的经典方法对失重状态下的游离气管插管进行评估。
NPJ Microgravity. 2023 Sep 8;9(1):73. doi: 10.1038/s41526-023-00314-y.
2
Anaesthesia in austere environments: literature review and considerations for future space exploration missions.严峻环境下的麻醉:文献综述及对未来太空探索任务的思考
NPJ Microgravity. 2018 Feb 23;4:5. doi: 10.1038/s41526-018-0039-y. eCollection 2018.

本文引用的文献

1
Technical innovations that may facilitate real-time telementoring of damage control surgery in austere environments: a proof of concept comparative evaluation of the importance of surgical experience, telepresence, gravity and mentoring in the conduct of damage control laparotomies.可能有助于在艰苦环境中对损伤控制手术进行实时远程指导的技术创新:一项关于手术经验、远程临场感、重力及指导在损伤控制剖腹手术操作中的重要性的概念验证性比较评估
Can J Surg. 2015 Jun;58(3 Suppl 3):S88-90. doi: 10.1503/cjs.014214.
2
The rate-limiting step: the provision of safe anesthesia in low-income countries.限速步骤:在低收入国家提供安全麻醉。
World J Surg. 2015 Apr;39(4):833-41. doi: 10.1007/s00268-014-2775-9.
3
Sedation for gastrointestinal endoscopy.
用于胃肠内镜检查的镇静
Endoscopy. 2014 Aug;46(8):720-31. doi: 10.1055/s-0034-1377561. Epub 2014 Jul 25.
4
Prioritizing essential surgery and safe anesthesia for the Post-2015 Development Agenda: operative capacities of 78 district hospitals in 7 low- and middle-income countries.为2015年后发展议程确定基本外科手术和安全麻醉的优先事项:7个低收入和中等收入国家78家区级医院的手术能力
Surgery. 2014 Mar;155(3):365-73. doi: 10.1016/j.surg.2013.10.008. Epub 2013 Oct 11.
5
Potential anesthesia protocols for space exploration missions.太空探索任务的潜在麻醉方案。
Aviat Space Environ Med. 2013 Mar;84(3):226-33. doi: 10.3357/asem.3427.2013.
6
Review article: safety aspects of anesthesia in under-resourced locations.综述文章:资源匮乏环境下麻醉的安全性问题。
Can J Anaesth. 2013 Feb;60(2):152-8. doi: 10.1007/s12630-012-9856-8. Epub 2012 Dec 11.
7
Perioperative and anaesthetic-related mortality in developed and developing countries: a systematic review and meta-analysis.发达国家和发展中国家围手术期和麻醉相关死亡率的系统评价和荟萃分析。
Lancet. 2012 Sep 22;380(9847):1075-81. doi: 10.1016/S0140-6736(12)60990-8.
8
Simulation in clinical teaching and learning.临床教学与学习中的模拟。
Med J Aust. 2012 May 21;196(9):594. doi: 10.5694/mja10.11474.
9
Is the Airtraq optical laryngoscope effective in tracheal intubation by novice personnel?Airtraq 可视喉镜对新手行气管插管是否有效?
Korean J Anesthesiol. 2010 Jul;59(1):17-21. doi: 10.4097/kjae.2010.59.1.17. Epub 2010 Jul 21.
10
The utility of simulation in medical education: what is the evidence?模拟在医学教育中的效用:证据是什么?
Mt Sinai J Med. 2009 Aug;76(4):330-43. doi: 10.1002/msj.20127.