维生素D对免疫反应的调节：在系统性红斑狼疮中的作用
Immune Response Modulation by Vitamin D: Role in Systemic Lupus Erythematosus.
作者信息
Iruretagoyena Mirentxu, Hirigoyen Daniela, Naves Rodrigo, Burgos Paula Isabel
机构信息
Departamento de Inmunología Clínica y Reumatología, Facultad de Medicina, Pontificia Universidad Católica de Chile , Santiago , Chile.
Programa de Inmunología, Instituto de Ciencias Biomédicas, Facultad de Medicina Universidad de Chile , Santiago , Chile.
出版信息
Front Immunol. 2015 Oct 12;6:513. doi: 10.3389/fimmu.2015.00513. eCollection 2015.
Vitamin D plays key roles as a natural immune modulator and has been implicated in the pathophysiology of autoimmune diseases, including systemic lupus erythematosus (SLE). This review presents a summary and analysis of the recent literature regarding immunoregulatory effects of vitamin D as well as its importance in SLE development, clinical severity, and possible effects of supplementation in disease treatment.
维生素D作为一种天然免疫调节剂发挥着关键作用，并与自身免疫性疾病（包括系统性红斑狼疮，SLE）的病理生理学相关。本综述对近期有关维生素D免疫调节作用及其在SLE发病、临床严重程度以及疾病治疗中补充维生素D可能产生的影响的文献进行了总结和分析。
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