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维生素D与系统性红斑狼疮:持续演变

Vitamin D and systemic lupus erythematosus: continued evolution.

作者信息

Yap Kristy S, Morand Eric F

机构信息

Rheumatology, Monash Health, Monash University, Melbourne, Victoria, Australia; Centre for Inflammatory Diseases, Monash University, Melbourne, Victoria, Australia.

出版信息

Int J Rheum Dis. 2015 Feb;18(2):242-9. doi: 10.1111/1756-185X.12489. Epub 2014 Dec 19.

Abstract

Vitamin D is a steroid hormone that has well-established roles in calcium and bone metabolism. Vitamin D has more recently become recognized for its role in the immune response and its potential immunomodulatory effects in autoimmune diseases, including systemic lupus erythematosus (SLE). This review provides a summary of the recent literature regarding vitamin D and SLE, as well as current recommendations for vitamin D supplementation in patients with SLE.

摘要

维生素D是一种类固醇激素,在钙和骨代谢中发挥着已被充分证实的作用。最近,维生素D在免疫反应中的作用及其在包括系统性红斑狼疮(SLE)在内的自身免疫性疾病中的潜在免疫调节作用也得到了认可。本文综述了近期关于维生素D与SLE的文献,以及目前对SLE患者补充维生素D的建议。

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