[肺曲霉病的实验模型]

[An experimental model of pulmonary aspergillosis].

作者信息

Morozov V L, Al'dzhambaeva I Sh, Khamitov S Kh, Akulov V D, Sitkovskiĭ G V

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1989 Jan(1):14-7.

Abstract

The model of experimental chronic pulmonary aspergillosis has been obtained in mice and guinea pigs by the intrapulmonary infection of the animals with the suspension of Aspergillus mycelium and spores in complete Freund's adjuvant. Such method of infection has made it possible to produce chronic local mycotic process. Morphologically, focal inflammatory changes of the lung tissue with the subsequent formation of a multitude of small abscesses in these areas have been observed as characteristic manifestations of aspergillosis.

摘要

通过将曲霉菌丝体和孢子悬浮于完全弗氏佐剂中对小鼠和豚鼠进行肺内感染，已建立了实验性慢性肺曲霉病模型。这种感染方法使得产生慢性局部真菌病过程成为可能。在形态学上，观察到肺组织的局灶性炎症变化，随后在这些区域形成大量小脓肿，这是曲霉病的特征性表现。