Jones M J
Department of Anaesthetics, University of Wales College of Medicine, Heath Park, Cardiff, U.K.
Acta Chir Scand Suppl. 1989;550:169-75; discussion 175-6.
The effect of anesthetic methods on mental function has been the subject of much discussion and debate over many years. Although it is commonly recognized that sedative, narcotic, and anesthetic agents have observable effects on cerebral function at the time of administration, more subtle and less easily detectable effects may persist into the postoperative period. Identifying and describing the effects of these drugs requires reliable and reproducible methods of measurement. The tests used for evaluating the effect of anesthetic methods on mental function are reviewed. The roles played by intraoperative and postoperative factors and their possible involvement in detectable decrement in mental function are described. Early postoperative effects of anesthetic methods on cognitive function are discussed, and the evidence for prolonged changes in mental function following anesthesia (particularly in the elderly) is reviewed.
多年来，麻醉方法对心理功能的影响一直是诸多讨论和争议的主题。尽管人们普遍认识到镇静剂、麻醉剂和麻醉药物在给药时对脑功能有明显影响，但更细微且不易察觉的影响可能会持续到术后阶段。识别和描述这些药物的影响需要可靠且可重复的测量方法。本文综述了用于评估麻醉方法对心理功能影响的测试。描述了术中及术后因素所起的作用及其可能与可检测到的心理功能减退的关联。讨论了麻醉方法对认知功能的早期术后影响，并综述了麻醉后（尤其是老年人）心理功能长期变化的证据。
