伏格特-小柳-原田综合征与克罗恩病：一种罕见的关联。
Vogt-Koyanagi-Harada syndrome and Crohn's disease: an exceptional association.
作者信息
Souguir Ahlem, Hammami Aya, Dahmeni Wafa, Jaziri Hanene, Ben Mansour Imed, Zayene Ahlem, Ben Slama Aida, Ksiaa Mehdi, Brahem Ahlem, Ajmi Salem, Jmaa Ali
机构信息
Department of Gastroenterology, University Hospital Sahloul, Sousse, Tunisia
Department of Gastroenterology, University Hospital Sahloul, Sousse, Tunisia.
出版信息
Gastroenterol Rep (Oxf). 2018 Feb 1;6(1):65-67. doi: 10.1093/gastro/gov056. Epub 2015 Nov 3.
Vogt-Koyanagi-Harada disease (VKH) is a rare, multisystem disease of melanocyte-containing organs. It is characterized by diffuse, granulomatous inflammation involving various organs. It has been reported to occur in association with other autoimmune disorders. We report the case of a female patient who was diagnosed with VKH at the age of 4 years and who was treated with corticosteroids until the age of 16. Twenty years later, Crohn's disease was diagnosed, with a severe flare-up. Three cases of VKH associated with ulcerative colitis have previously been reported anecdotally but, to our knowledge, this is the first case occurring in association to Crohn's disease.
伏格特-小柳-原田病（VKH）是一种罕见的累及含黑素细胞器官的多系统疾病。其特征为累及多个器官的弥漫性肉芽肿性炎症。据报道，它可与其他自身免疫性疾病相关。我们报告一例女性患者，该患者4岁时被诊断为VKH，并接受皮质类固醇治疗直至16岁。20年后，诊断为克罗恩病，病情严重发作。此前曾有3例VKH与溃疡性结肠炎相关的个案报道，但据我们所知，这是首例与克罗恩病相关的病例。
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