Fram Brandon, Fernandez Andrew, Syed Huzaefah, Brar Vikram
Department of Ophthalmology, Virginia Commonwealth University Health System, Richmond, VA, USA.
Department of Rheumatology, Virginia Commonwealth University Health System, Richmond, VA, USA.
Am J Ophthalmol Case Rep. 2022 Jun 18;27:101625. doi: 10.1016/j.ajoc.2022.101625. eCollection 2022 Sep.
To report diffuse orbital inflammation as a manifestation of recurrent inflammation in a patient with Vogt-Koyanagi-Harada (VKH) disease.
20-year-old African American male, who was previously diagnosed with VKH, presented with right eye pain, swelling, and binocular double vision. He had run out of methotrexate while on steroid taper. Neuroimaging was consistent with diffuse orbital inflammation with myositis. He was started on intravenous steroids and then transitioned to oral steroids, with complete resolution of his symptoms.
Central nervous system involvement as a manifestation of VKH has been previously reported, however, there have been no reports of orbital inflammatory syndrome resulting from VKH. Thus, in the appropriate clinical context, orbital signs may be recognized as features of recurrent VKH.
报告1例Vogt-小柳-原田（VKH）病患者出现弥漫性眼眶炎症作为复发炎症的一种表现。
一名20岁非裔美国男性，既往诊断为VKH，出现右眼疼痛、肿胀及双眼复视。在逐渐减少类固醇用量时他的甲氨蝶呤已用完。神经影像学检查结果与伴有肌炎的弥漫性眼眶炎症相符。他开始接受静脉注射类固醇治疗，随后转为口服类固醇，症状完全缓解。
先前已有关于VKH表现为中枢神经系统受累的报道，然而，尚无VKH导致眼眶炎性综合征的报道。因此，在适当的临床背景下，眼眶体征可被视为复发性VKH的特征。
