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[反复使用抗菌油乳剂疫苗后年轻母鸡的淀粉样变性发作]

[Episodes of amyloidosis in young hens after repeated use of antibacterial oil emulsion vaccines].

作者信息

Rampin T, Sironi G, Gallazzi D

出版信息

Dtsch Tierarztl Wochenschr. 1989 Apr;96(4):168, 170, 172.

PMID:2653772
Abstract

Outbreaks of systemic amyloidosis with moderate to high mortality in two young layer flocks are described. In both the cases anamnesis reported repeated vaccinations with oil-emulsified bacterins. Grossly, the liver was enlarged, friable and pale. Hepatic rupture and haemorrhages were frequently seen. Moreover heavy granulomatous reactions at the inoculation site was observed. Histologically amyloid deposition was present in the liver and the spleen of the animals from both of the flocks. Histochemical reactions confirm that it is type AA amyloidosis.

摘要

本文描述了两个年轻蛋鸡群中发生的具有中度至高死亡率的系统性淀粉样变疫情。在这两个病例中,病史报告显示曾多次接种油乳剂菌苗。大体上,肝脏肿大、质脆且苍白。经常可见肝破裂和出血。此外,在接种部位观察到严重的肉芽肿反应。组织学检查发现,两个鸡群的动物肝脏和脾脏中均存在淀粉样物质沉积。组织化学反应证实这是AA型淀粉样变。

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