Ruan Huijuan, Xun Pengcheng, Cai Wei, He Ka, Tang Qingya
Department of Clinical Nutrition, Xin Hua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Department of Epidemiology and Biostatistics, School of Public Health-Bloomington, Indiana University, Bloomington, IN, USA.
Sci Rep. 2015 Nov 5;5:16160. doi: 10.1038/srep16160.
A meta-analysis of cross-sectional studies found that shorter-time sleep was correlated with increased risk of obesity in children. However, findings from prospective cohort studies were inconsistent. PubMed and other data resources were searched through May 2015. Twenty-five eligible studies were identified including 56,584 children and adolescents with an average 3.4-year follow-up. Compared with children having the longest sleep duration (12.2 hours), kids with the shortest sleep duration (10.0 hours) were 76% more likely to be overweight/obese (pooled odds ratio [OR]: 1.76; 95% confidence interval [CI]: 1.39, 2.23); and had relatively larger annual BMI gain (pooled β coefficient: 0.13; 95% CI: 0.01, 0.25 kg/m(2)). With every 1 hour/day increment in sleep duration, the risk of overweight/obesity was reduced by 21% (OR: 0.79; 95% CI: 0.70, 0.89); and the annual BMI gain declined by 0.05 kg/m(2) (β = -0.05; 95% CI: -0.09, -0.01). The observed associations were not appreciably modified by region, baseline age or the length of follow-up. Accumulated literature indicates a modest inverse association between sleep duration and the risk of childhood overweight/obesity. Further research is needed to determine the age and gender specified optimal hours of sleep and ideal sleep pattern with respect to obesity prevention in children.
一项横断面研究的荟萃分析发现，睡眠时间较短与儿童肥胖风险增加相关。然而，前瞻性队列研究的结果并不一致。检索了截至2015年5月的PubMed及其他数据资源。确定了25项符合条件的研究，包括56,584名儿童和青少年，平均随访3.4年。与睡眠时间最长（约12.2小时）的儿童相比，睡眠时间最短（约10.0小时）的儿童超重/肥胖的可能性高76%（合并比值比[OR]：1.76；95%置信区间[CI]：1.39, 2.23）；且每年BMI增加相对较大（合并β系数：0.13；95% CI：0.01, 0.25 kg/m²）。睡眠时间每增加1小时/天，超重/肥胖风险降低21%（OR：0.79；95% CI：0.70, 0.89）；每年BMI增加下降0.05 kg/m²（β = -0.05；95% CI：-0.09, -0.01）。观察到的关联未因地区、基线年龄或随访时间长短而有明显改变。累积文献表明睡眠时间与儿童超重/肥胖风险之间存在适度的负相关。需要进一步研究以确定针对儿童肥胖预防的特定年龄和性别的最佳睡眠时间及理想睡眠模式。
